Pausing GLP-1 drugs before colonoscopy: could a One-Week break improve bowel prep?

NCT ID NCT07736963

Recruiting now Knowledge-focused Sponsor: Fu Jen Catholic University Hospital Source: ClinicalTrials.gov ↗

First seen Jul 30, 2026 · Last updated Jul 31, 2026 · Updated 1 time

Summary

This trial tests whether stopping GLP-1 receptor agonists (medications like semaglutide and liraglutide) for one week before a colonoscopy leads to better bowel preparation and fewer repeat procedures. Researchers will compare bowel cleanliness and detection rates of polyps between people who pause the drug and those who continue it. The study includes adults aged 18 to 70 scheduled for a colonoscopy, aiming to establish clear discontinuation recommendations.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: GLP-1 receptor agonists (drugs like semaglutide and liraglutide)
What this could lead to: If it works, this could lead to clear guidelines on when to pause GLP-1 drugs before colonoscopy, improving procedure success and patient experience.
What could go wrong: This is a small, early-stage trial focused on a procedural question, not a new treatment. Results may not apply to all GLP-1 users or colonoscopy settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GLP-1

Contacts and locations

Locations

FJUH
RECRUITING

New Taipei, Taiwan, 24352, Taiwan

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