Multivitamins may protect against nutrient loss in GLP-1 users

NCT ID NCT07234916

ENROLLING_BY_INVITATION Disease control Sponsor: Erasmus Medical Center Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether taking a daily multivitamin can prevent vitamin and mineral deficiencies in people using GLP-1 drugs (like tirzepatide) for weight loss. About 246 adults with obesity who have been on a stable GLP-1 dose for at least 3 months will be randomly assigned to receive either a multivitamin or a placebo for 12 months. Researchers will measure key nutrients like vitamin B12, vitamin D, and iron in the blood to see if supplementation makes a difference.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: multivitamin supplement
What this could lead to: If it works, this could show that taking a daily multivitamin helps prevent nutrient deficiencies in people using GLP-1 weight-loss drugs.
What could go wrong: This is a small, early-stage trial focused on blood levels, not on preventing actual health problems. The results may not apply to everyone, and multivitamins might not make a meaningful difference.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Malnutrition nutritional deficiency disease Obesity obesity disorder Weight Loss

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GLP-1 NUTRITIONAL DEFICIENCIES OBESE PATIENTS WEIGHT LOSS

Contacts and locations

Locations

Erasmus MC

Rotterdam, Netherlands
WeightWorks Clinics

Amersfoort, Netherlands

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