METABOLIC SYNDROME
Clinical trials for METABOLIC SYNDROME explained in plain language.
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Cooking oil swap tested to tame heart disease risk factors
Disease control CompletedThis study tested whether using canola oil instead of typical fats for 12 weeks could improve health markers in people with metabolic syndrome. Metabolic syndrome is a cluster of conditions like high blood pressure and high cholesterol that increase heart disease risk. Researcher…
Matched conditions: METABOLIC SYNDROME
Phase: NA • Sponsor: University of Manitoba • Aim: Disease control
Last updated Apr 03, 2026 14:42 UTC
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Can free healthy meals and group coaching help fight heart disease and diabetes?
Disease control CompletedThis study tested whether delivering healthy, culturally appropriate meals, with or without weekly group coaching sessions, could help people manage conditions like high blood pressure, type 2 diabetes, and obesity. It involved 75 Black adults from a specific Cleveland community.…
Matched conditions: METABOLIC SYNDROME
Phase: NA • Sponsor: Amanda Shallcross • Aim: Disease control
Last updated Apr 03, 2026 14:41 UTC
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Can a daily strawberry habit tame high cholesterol?
Disease control CompletedThis study tested whether eating strawberry powder daily could improve heart and metabolic health in overweight or obese adults with borderline high cholesterol. Forty-eight participants tried three different daily amounts of strawberry powder for four weeks each, with breaks in …
Matched conditions: METABOLIC SYNDROME
Phase: NA • Sponsor: Carl Ade, M.S., Ph.D. • Aim: Disease control
Last updated Apr 03, 2026 14:41 UTC
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Intensive lifestyle program aims to turn back the clock on metabolic syndrome
Disease control CompletedThis study tested whether a structured, intensive lifestyle program could help overweight or obese adults with metabolic syndrome achieve significant weight loss and reverse their condition. 68 participants followed either an intensive low-carb diet and exercise plan or a standar…
Matched conditions: METABOLIC SYNDROME
Phase: NA • Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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Eating window timing tested for weight and health boost
Disease control CompletedThis study compared two types of time-restricted eating schedules in overweight adults with metabolic syndrome. Researchers tested whether eating earlier in the day or later in the day was more effective for improving health. They measured changes in body weight, abdominal fat, b…
Matched conditions: METABOLIC SYNDROME
Phase: NA • Sponsor: First Affiliated Hospital Xi'an Jiaotong University • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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Could hydrogen water shrink your waistline?
Disease control CompletedThis study tested whether drinking hydrogen-rich water for 12 weeks could help improve body composition and blood markers in adults with metabolic syndrome. Forty participants were randomly assigned to drink either the hydrogen water or a placebo. The goal was to see if this simp…
Matched conditions: METABOLIC SYNDROME
Phase: NA • Sponsor: University of Novi Sad, Faculty of Sport and Physical Education • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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Could a common pill protect the hearts of millions with obesity?
Disease control CompletedThis study tested if a medication called eplerenone could improve heart health in overweight or obese people with high blood pressure or related conditions. It compared eplerenone to another standard blood pressure drug to see which was better at improving blood flow and reducing…
Matched conditions: METABOLIC SYNDROME
Phase: PHASE4 • Sponsor: Brigham and Women's Hospital • Aim: Disease control
Last updated Mar 30, 2026 14:34 UTC
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App aims to help kids fight obesity from home
Disease control CompletedThis study tested a new digital care approach for families with children living with obesity in Sweden. It compared standard in-person clinic visits to a program that replaced half the visits with a smartphone app for tracking health goals and communicating with caregivers. The g…
Matched conditions: METABOLIC SYNDROME
Phase: NA • Sponsor: Göteborg University • Aim: Disease control
Last updated Mar 30, 2026 14:29 UTC
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Home leg stimulation plus diet tested to fight metabolic problems after spinal injury
Disease control CompletedThis study tested if a 16-week home program combining leg stimulation exercise with a diet plan was better than diet alone for improving health in adults with spinal cord injuries. Researchers measured changes in body fat, insulin sensitivity, and metabolism. The goal was to see …
Matched conditions: METABOLIC SYNDROME
Phase: NA • Sponsor: University of Miami • Aim: Disease control
Last updated Mar 30, 2026 14:28 UTC
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New hope for hidden heart risk? drug trial targets silent blood flow problem
Disease control CompletedThis study tested whether a drug called vericiguat could improve the function of tiny blood vessels in the heart for people with metabolic syndrome, a cluster of conditions like high blood pressure and high blood sugar. Forty-five participants were randomly assigned to receive ei…
Matched conditions: METABOLIC SYNDROME
Phase: PHASE2 • Sponsor: Johns Hopkins University • Aim: Disease control
Last updated Mar 27, 2026 12:41 UTC
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Ancient 'Miracle Tree' put to the test for modern health problems
Disease control CompletedThis study tested whether taking capsules of Moringa oleifera leaf powder could improve key health markers in adults with metabolic syndrome, a cluster of conditions like high blood pressure and high blood sugar. For 8 weeks, 36 participants took either the Moringa powder or a pl…
Matched conditions: METABOLIC SYNDROME
Phase: NA • Sponsor: Universidad de Colima • Aim: Disease control
Last updated Mar 27, 2026 12:40 UTC
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Can herbal teas tame metabolic syndrome?
Disease control CompletedThis study tested whether drinking two different herbal tea blends could improve health markers in adults with metabolic syndrome. Thirty overweight adults drank either a 'VitalPLANT' tea or a combination of VitalPLANT and Helichrysum italicum tea daily for one week. Researchers …
Matched conditions: METABOLIC SYNDROME
Phase: NA • Sponsor: University of Primorska • Aim: Disease control
Last updated Mar 27, 2026 12:38 UTC
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Community program tested to fight diabetes in navajo nation
Disease control CompletedThis study looked at a community health program called COPE that has been running in the Navajo Nation since 2009. It aimed to see if the program helped people with diabetes better manage their condition by improving blood sugar, blood pressure, and other health measures. Researc…
Matched conditions: METABOLIC SYNDROME
Sponsor: Brigham and Women's Hospital • Aim: Disease control
Last updated Mar 27, 2026 12:38 UTC
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Doctors test 'Smart' program that adjusts treatment for weight and blood sugar issues
Disease control CompletedThis study tested a flexible lifestyle program for people with conditions like insulin resistance, obesity, or prediabetes. It started with either nutrition or exercise counseling. If a person's insulin resistance didn't improve enough after 8 weeks, the program could switch them…
Matched conditions: METABOLIC SYNDROME
Phase: NA • Sponsor: University of Alabama at Birmingham • Aim: Disease control
Last updated Mar 25, 2026 14:08 UTC
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Common diabetes drug tested to protect HIV Patients' brains
Disease control CompletedThis small pilot study tested whether metformin, a common and affordable diabetes medication, could improve blood vessel function and blood flow in the brains of people living with HIV who also have metabolic syndrome. The researchers enrolled 30 participants in South Africa who …
Matched conditions: METABOLIC SYNDROME
Phase: PHASE2 • Sponsor: University of Stellenbosch • Aim: Disease control
Last updated Mar 25, 2026 14:07 UTC
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Can a cup of green tea fix your gut and fight inflammation?
Disease control CompletedThis study tested whether taking a green tea extract supplement for one month could improve gut health and reduce harmful inflammation in people with metabolic syndrome, a cluster of conditions like high blood pressure and high blood sugar. Forty-six participants, including some …
Matched conditions: METABOLIC SYNDROME
Phase: NA • Sponsor: Ohio State University • Aim: Disease control
Last updated Mar 23, 2026 15:19 UTC
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Ancient seed tested to tame modern health woes in midlife women
Disease control CompletedThis study tested whether a daily supplement made from black seed (Nigella sativa) could help improve health markers and quality of life for perimenopausal women with metabolic syndrome. Fifty women were randomly assigned to take the supplement or follow a Mediterranean diet for …
Matched conditions: METABOLIC SYNDROME
Phase: NA • Sponsor: Liaquat University of Medical & Health Sciences • Aim: Disease control
Last updated Mar 23, 2026 15:14 UTC
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Head-to-Head: which PCOS treatment works best?
Disease control CompletedThis study directly compared four common approaches for managing Polycystic Ovary Syndrome (PCOS) over 12 weeks. Researchers assigned 192 women with PCOS to take either metformin, inositol supplements, follow a calorie-restricted diet, or use all three treatments combined. The go…
Matched conditions: METABOLIC SYNDROME
Phase: NA • Sponsor: Islamabad Medical and Dental College • Aim: Disease control
Last updated Mar 20, 2026 14:48 UTC
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Could a milk ingredient fix your gut and lower blood sugar?
Disease control CompletedThis study tested whether adding a natural component from milk fat (MFGM) to the diet could help adults with metabolic syndrome. Participants drank either the special milk or a regular milk for two weeks while eating a controlled diet. Researchers measured blood sugar, gut health…
Matched conditions: METABOLIC SYNDROME
Phase: NA • Sponsor: Ohio State University • Aim: Disease control
Last updated Mar 13, 2026 15:05 UTC
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Can a 12-Week diet plan prevent diabetes in women?
Prevention CompletedThis study tested a 12-week diet and lifestyle program called the SWW Method to see if it could help women improve their blood sugar levels and manage their weight. The program included guidance on fasting, meal timing, and protein-focused eating. Researchers compared 45 women wh…
Matched conditions: METABOLIC SYNDROME
Phase: NA • Sponsor: Sarah Wragge Wellness • Aim: Prevention
Last updated Apr 01, 2026 14:42 UTC
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Exercise pill combo could block heart disease
Prevention CompletedThis study aimed to find the best combination of exercise intensity and the common diabetes drug metformin to improve blood vessel function and insulin sensitivity in adults with metabolic syndrome. Researchers tested whether high or low-intensity exercise worked better with metf…
Matched conditions: METABOLIC SYNDROME
Phase: PHASE2, PHASE3 • Sponsor: Rutgers University • Aim: Prevention
Last updated Mar 30, 2026 14:29 UTC
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Does your health profile change how well a back pain shot works?
Symptom relief CompletedThis study looked at whether having metabolic syndrome (a cluster of conditions like high blood pressure and high blood sugar) changes how well a steroid injection works for chronic back and leg pain from a herniated disc. Researchers gave the injection to 51 adults whose pain ha…
Matched conditions: METABOLIC SYNDROME
Phase: NA • Sponsor: Marmara University • Aim: Symptom relief
Last updated Apr 03, 2026 21:41 UTC
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Can cutting junk food help ease depression? small study tests the idea
Symptom relief CompletedThis small pilot study explored whether it's practical and acceptable for people with depression to reduce the amount of ultra-processed foods in their diet. Researchers worked with 20 adults who had major depressive disorder and typically ate a lot of processed foods. The main g…
Matched conditions: METABOLIC SYNDROME
Phase: NA • Sponsor: University of California, San Francisco • Aim: Symptom relief
Last updated Apr 03, 2026 14:43 UTC
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Scientists revisit 18 people after 16 years to solve a metabolic mystery
Knowledge-focused CompletedThis study aims to understand if the body's ability to efficiently switch between using sugars and fats for energy (called metabolic flexibility) influences long-term health risks like obesity and metabolic syndrome. Researchers are recalling 18 healthy participants from a study …
Matched conditions: METABOLIC SYNDROME
Sponsor: Pennington Biomedical Research Center • Aim: Knowledge-focused
Last updated Apr 03, 2026 14:43 UTC
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Do HIV drugs cause other health problems? major study tracks patients for answers
Knowledge-focused CompletedThis study aimed to understand and compare the long-term health risks associated with different HIV drug treatments. Researchers followed 215 newly diagnosed, treatment-naive HIV patients in Hong Kong for up to five years after they started medication. They tracked the developmen…
Matched conditions: METABOLIC SYNDROME
Sponsor: Chinese University of Hong Kong • Aim: Knowledge-focused
Last updated Apr 03, 2026 14:43 UTC
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Scientists track SCI patients for a year to uncover hidden causes of weight gain
Knowledge-focused CompletedThis study aimed to understand why people with spinal cord injuries (SCI) often gain weight after leaving the hospital. Researchers followed 42 adults with recent SCI for one year after their rehab stay, checking in at discharge, 6 months, and 12 months. They collected informatio…
Matched conditions: METABOLIC SYNDROME
Sponsor: Baylor Research Institute • Aim: Knowledge-focused
Last updated Apr 03, 2026 14:41 UTC
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Can a special drink give your brain a new fuel source?
Knowledge-focused CompletedThis study tested whether a ketone ester drink could change how the brain uses energy and improve thinking skills. It involved 99 adults aged 55 and older who had metabolic syndrome but normal memory. Participants drank either the ketone supplement or a placebo three times a day …
Matched conditions: METABOLIC SYNDROME
Phase: NA • Sponsor: National Institute on Aging (NIA) • Aim: Knowledge-focused
Last updated Apr 03, 2026 14:41 UTC
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Blood test may predict who benefits most from weight loss surgery
Knowledge-focused CompletedThis study looked at whether measuring a specific protein (PTX3) in the blood before surgery could help predict how well patients would respond to weight loss surgery. Researchers followed 23 patients undergoing gastric bypass surgery, checking their weight, insulin resistance, a…
Matched conditions: METABOLIC SYNDROME
Sponsor: Istanbul University • Aim: Knowledge-focused
Last updated Apr 03, 2026 14:41 UTC
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Your genes may hold the key to the right diet for metabolic health
Knowledge-focused CompletedThis study aimed to see if a score based on a person's genetics could predict how well they respond to a specific low-fat diet. Researchers enrolled 115 adults with metabolic syndrome in Mexico. Participants followed the recommended diet for two months while researchers tracked c…
Matched conditions: METABOLIC SYNDROME
Phase: NA • Sponsor: Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran • Aim: Knowledge-focused
Last updated Apr 02, 2026 14:56 UTC
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Is orange juice really better than soda? science weighs in
Knowledge-focused CompletedThis study aimed to understand if drinking orange juice has different effects on heart and diabetes risk factors compared to sugary drinks like soda. Researchers had 56 normal-weight and overweight adults drink either orange juice or a sugar-sweetened beverage daily for four week…
Matched conditions: METABOLIC SYNDROME
Phase: NA • Sponsor: University of California, Davis • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:43 UTC
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Scientists search for better warning signs of heart risk in obesity
Knowledge-focused CompletedThis study aimed to find the best measurements for predicting metabolic syndrome in people with obesity. Researchers analyzed data from 332 adults, comparing standard body measurements with newer calculations based on waist size and blood tests. The goal was to identify which ind…
Matched conditions: METABOLIC SYNDROME
Sponsor: Tokat Gaziosmanpasa University • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:41 UTC
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Can a simple fat test predict your heart attack risk?
Knowledge-focused CompletedThis study aimed to see if measuring how the body handles fats (triglycerides) could help identify which patients with stable heart disease are at higher risk for future heart problems. Researchers followed 514 people with coronary artery disease for 18 months, tracking their tri…
Matched conditions: METABOLIC SYNDROME
Sponsor: Universität des Saarlandes • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:28 UTC
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Scientists probe fat cells to unlock Surgery's secret health boost
Knowledge-focused CompletedThis study aimed to understand why weight loss surgery improves the body's ability to manage blood sugar so quickly, often before significant weight loss occurs. Researchers studied 28 women, comparing fat cells from those with and without obesity before and after surgery. They l…
Matched conditions: METABOLIC SYNDROME
Phase: NA • Sponsor: University of Chicago • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:39 UTC
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Scientists scan bellies to uncover heart disease link
Knowledge-focused CompletedThis study aimed to better understand how excess belly fat relates to the buildup of fatty plaques in arteries, which can lead to heart attacks. Researchers used MRI and CT scans to measure fat distribution and artery plaque in 357 healthy adults aged 35-65. The goal was to gathe…
Matched conditions: METABOLIC SYNDROME
Sponsor: Laval University • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:39 UTC
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Could your waistline predict your shoulder pain?
Knowledge-focused CompletedThis study followed 1100 people with shoulder pain for up to 5 years to understand what factors lead to long-lasting pain. Researchers specifically wanted to see if having metabolic syndrome (a cluster of conditions like high blood pressure and excess belly fat) makes shoulder pa…
Matched conditions: METABOLIC SYNDROME
Sponsor: Vejle Hospital • Aim: Knowledge-focused
Last updated Mar 25, 2026 14:08 UTC
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Scientists probe hidden link between HIV, inflammation, and Aging-Related diseases
Knowledge-focused CompletedThis study aimed to understand why people living with HIV are at higher risk for other health problems like heart disease and diabetes, even when their virus is controlled by medication. Researchers followed 320 Chilean patients, with and without metabolic syndrome, to collect de…
Matched conditions: METABOLIC SYNDROME
Sponsor: Universidad de Magallanes • Aim: Knowledge-focused
Last updated Mar 25, 2026 14:07 UTC
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Does diabetes change your risk of catching malaria?
Knowledge-focused CompletedThis study aimed to understand if having type 2 diabetes changes a person's risk of getting malaria and other parasitic worm infections. Researchers in Cameroon followed 406 adults, some with diabetes and some without, for one year. They tested blood and stool samples regularly t…
Matched conditions: METABOLIC SYNDROME
Sponsor: Karolinska Institutet • Aim: Knowledge-focused
Last updated Mar 24, 2026 12:03 UTC
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Could vitamin d levels predict metabolic health in seniors?
Knowledge-focused CompletedThis study looked at whether higher vitamin D levels are linked to a lower risk of metabolic syndrome (a cluster of conditions like high blood pressure and insulin resistance) in older adults who do not have a vitamin D deficiency. Researchers surveyed nearly 2,000 community-dwel…
Matched conditions: METABOLIC SYNDROME
Sponsor: National Cheng-Kung University Hospital • Aim: Knowledge-focused
Last updated Mar 19, 2026 14:55 UTC
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Scientists track how diet and exercise change your Body's inner workings
Knowledge-focused CompletedThis study aimed to understand how a 12-month lifestyle program affects body fat and specific gene activity in adults with metabolic syndrome. Researchers followed 50 participants, tracking their weight, body composition, and blood markers at the start, 6 months, and 12 months. P…
Matched conditions: METABOLIC SYNDROME
Phase: NA • Sponsor: Aga Khan University • Aim: Knowledge-focused
Last updated Feb 18, 2026 14:07 UTC