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Junk food & depression: can ditching processed foods lift mood?

NCT ID NCT06252701

Knowledge-focused Sponsor: University of California, San Francisco Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This small pilot study looked at whether people with major depression who eat a lot of ultra-processed foods could cut back on them. Twenty adults tried a personalized plan to reduce these foods. The goal was to see if it was possible and acceptable, not to measure mood changes. Results suggest it may be doable, but larger studies are needed to know if it helps depression.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

20 people

The number who actually took part.

Started

Jun 2024

Finished

Jun 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 18-80 year olds (inclusive), all race/ethnic groups * Willing to not change psychotropic medication or psychotherapy regimen during the study * Willing and able to come to UCSF for in person visits two times * Ability to speak and read English and answer participant surveys Exclusion Criteria: * Psychiatric hospitalization in past 3 months * Active suicidal ideation with intent and plan or scoring a 3 or higher on the Columbia suicide severity rating scale (C-SSRS) * In a current severe mood state when entering the study that would prohibit compliance with study visits or dietary program * Known GI abnormalities or known GI medical problems (diarrhea, chronic intestinal disease, toxic megacolon, ileum) or known swallowing or chewing disorders or issues * Anticipating or planning any major changes in physical activity or sleep during the study * Pregnant or planning to be pregnant during the study * Breastfeeding or planning to breastfeed during the study

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Conditions

The condition(s) this trial relates to.

abdominal obesity-metabolic syndrome Depression depressive disorder major depressive disorder metabolic syndrome X Obesity obesity disorder Weight Gain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Depression Major depressive disorder Metabolic syndrome Obesity Weight gain

Contacts and locations

Locations

  • University of California, San Francisco

    San Francisco, California, 94107, United States

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