WEIGHT GAIN

This study tests whether a very low dose of semaglutide (a drug used for weight loss and diabetes) can help people with HIV maintain weight loss and improve heart health. Thirty participants will first receive a standard dose for 12 weeks, then half will get a low maintenance dos…

This study looks at whether replacing sugary drinks with stevia-sweetened ones helps children ages 8 to 12 control their weight, blood sugar, and cholesterol. About 150 kids who currently drink sugary beverages will be assigned to drink either stevia-sweetened drinks, water, or s…

This study looks at people who had a gastric bypass but later regained weight or didn't lose enough. It compares two different ways to do a second surgery (distal gastric bypass) to see which works better for weight loss and has fewer side effects like diarrhea. About 150 adults …

This study looks at whether limiting when you eat each day (time-restricted eating) can help adults who have recently lost weight keep it off and avoid regaining fat. About 110 adults aged 25-65 who lost at least 5% of their body weight in the last 3 months will be randomly assig…

This study tests a once-weekly medicine called tirzepatide in 300 teens with obesity and at least two weight-related health issues like high blood pressure or prediabetes. Participants receive the drug or a placebo along with healthy eating and exercise advice for about 76 weeks.…

This study looks at 250 women who have had early-stage breast cancer and now struggle with both insomnia and being overweight. Researchers want to see if a special sleep therapy before a weight loss program helps them lose more weight than just learning about sleep. The goal is t…

This study looks at how high-intensity interval training (HIIT) changes brain activity and appetite in people who regained weight after bariatric surgery. Researchers will use brain scans and questionnaires to understand the connection between exercise, brain function, and weight…

This study looks at whether having groceries delivered can help low-income pregnant young women gain a healthy amount of weight and eat better. About 570 women in early pregnancy will take part. The goal is to learn if this simple support can make a difference.

This study aims to understand why some HIV drugs cause weight gain. Healthy volunteers aged 18 to 55 will take one of four HIV medications for 4 weeks. Researchers will measure changes in blood, fat tissue, and metabolism to find early signs of weight gain.