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HIV drug showdown: which regimen causes fewer side effects?

NCT ID NCT03483584

Knowledge-focused Sponsor: Chinese University of Hong Kong Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study followed 215 people newly diagnosed with HIV in Hong Kong to see how often they developed non-AIDS conditions like high blood pressure, diabetes, bone thinning, and kidney problems. Participants were on different anti-retroviral regimens, and researchers compared the rates of these conditions between those taking integrase inhibitor-based drugs and those on other treatments. The goal was to understand which treatment might be safer in the long run.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

215 people

The number who actually took part.

Started

Apr 2018

Finished

Sep 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

All newly diagnosed HIV-infected patients meeting inclusion criteria, who attend the government HIV clinic, which is the largest HIV clinic in Hong Kong, over a 12-month period, will be invited to participate in this study. Subjects will also be referred by non-governmental organizations providing support to HIV-infected individuals at the time of diagnosis.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Confirmed HIV infection by HIV antibody or RNA test 2. Age ≥18 years old 3. Anti-retroviral treatment naïve 4. Agree to initiate anti-retroviral therapy (ART) as determined by in-charge HIV physician Exclusion Criteria: 1. Pregnancy 2. Unable to give informed consent

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Conditions

The condition(s) this trial relates to.

abdominal obesity-metabolic syndrome Bone Diseases, Metabolic cirrhosis of liver fibrotic liver disease HIV infectious disease impaired renal function disease kidney failure metabolic syndrome X osteoporosis vitamin D deficiency

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HIV Liver fibroses Metabolic syndrome Osteopenia Osteoporosis Renal impairment Vitamin D deficiency

Contacts and locations

Locations

  • Prince of Wales Hospital

    Shatin, Hong Kong

More trials for these conditions

Other studies related to the condition(s) this trial covers.