Belly fat linked to artery plaque in new imaging study
NCT ID NCT01447745
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This completed study looked at 357 healthy adults aged 35-65 to understand how excess belly fat relates to the buildup of fatty plaque in arteries, a key cause of heart attacks. Using MRI and CT scans, researchers measured abdominal fat and artery wall thickness. The goal was to clarify why body shape matters more than body size for heart disease risk, potentially leading to better prevention strategies.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this research could lead to better ways to identify people at risk for heart disease based on belly fat rather than just body weight.
- What could go wrong
- This is an observational study, not a treatment trial, so it won't directly test any therapy. Results may not lead to immediate clinical changes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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357 people
The number who actually took part.
- Started
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Mar 2013
- Finished
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Feb 2020
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Random sample of adult men and women representative of the population of asymptomatic adult men and women aged from 35-65 years living in the Québec City metropolitan area
- Ages
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35 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Men and women aged 35-65 years Exclusion Criteria: * Massive obesity (BMI ≥ 40 kg/m2) * Pharmacological treatment for lipids, hypertension and/or type 2 diabetes * Clinical signs of cardiovascular disease * Chronic inflammatory or auto-immune diseases * Pulmonary diseases on corticosteroids * Cancers not in remission * History or clinical evidence of coronary heart disease (CHD) * History of revascularisation procedures * Current smoking * Hormonal replacement therapy
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Institut universitaire de cardiologie et de pneumologie de Québec
Québec, G1V 4G5, Canada
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