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Exercise plus metformin: a new hope for metabolic syndrome?

NCT ID NCT03355469

First seen Nov 01, 2025 · Last updated May 19, 2026 · Updated 27 times

Summary

This study looked at whether combining different doses of exercise with the diabetes drug metformin can improve blood vessel function and insulin sensitivity in adults with metabolic syndrome. 91 participants were assigned to high- or low-intensity exercise, with or without metformin, for 16 weeks. The goal was to find the best way to prevent type 2 diabetes and heart disease in this high-risk group.

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Contacts and locations

Locations

  • Rutgers University Loree Gymnasium

    New Brunswick, New Jersey, 08901, United States

Conditions

Explore the condition pages connected to this study.