METABOLIC SYNDROME

This study aims to find out if patients who continue taking their GLP-1 weight loss and diabetes medications (like Wegovy or Ozempic) after bariatric surgery have better results than those who stop. Researchers will compare weight loss, blood sugar control, and other health facto…

This study is testing whether a specific nutritional supplement, taken alongside dietary advice, can help manage the symptoms of Polycystic Ovary Syndrome (PCOS). Researchers will enroll 120 women with PCOS to see if the supplement improves hormone levels, reduces inflammation, a…

This study is testing if a drug called empagliflozin, usually used for diabetes, can help control weight gain and improve heart health in people living with HIV. It will involve 66 adults with HIV who are overweight and on a specific antiviral treatment. Researchers will measure …

This study is testing if limiting daily eating to a specific 8 or 10-hour window can improve health for people with metabolic syndrome, a cluster of conditions that raise heart disease and diabetes risk. Researchers are also testing if adding psychological and educational support…

This study is testing whether a type of dietary fiber called resistant starch can improve heart health and gut bacteria in women with Polycystic Ovary Syndrome (PCOS). 100 women with PCOS will take either the resistant starch or a placebo (inactive substance) for 12 weeks. Resear…

This study is testing whether the speed at which people lift weights affects their kidney health after a transplant. Researchers will compare fast, explosive lifting to slower, controlled lifting over 12 weeks. The goal is to see if one type of exercise is better at helping maint…

This study is testing whether drinking a cranberry beverage for 12 weeks can improve blood sugar control, cholesterol levels, and the balance of gut bacteria in overweight or obese adults. Participants will drink either the cranberry drink or a placebo for two separate periods, w…

This study is testing whether a program of intermittent fasting, calorie reduction, and increased physical activity can improve key health markers in adults with metabolic syndrome. Researchers in Saudi Arabia will compare this combined lifestyle program to standard hospital care…

This study is testing if limiting daily eating to an 8-12 hour window can improve long-term health for people with metabolic syndrome, a condition that increases the risk of heart disease and diabetes. Over 54 weeks, 140 participants will either follow this time-restricted eating…

This study is testing a new, less invasive stomach procedure to help with weight loss. It compares a new clip-and-loop method that shrinks the stomach size against a strong diet and exercise program. The goal is to see if this procedure is a safe and effective option for Chinese …

This study is testing if adding aerobic exercise, like walking on a treadmill, to standard talk therapy (Cognitive Behavioural Treatment) is more helpful for men. It aims to help 40 men in Egypt who struggle with heavy drinking, impotence, and a cluster of health issues called me…

This study is testing whether a lifestyle program combining a Mediterranean diet, reduced calories, and physical activity can help middle-aged adults with metabolic syndrome lose weight and improve their heart health markers. Researchers will compare this program to standard heal…

This study is testing if a combination of gentle electrical skin stimulation and handgrip exercises can help lower blood pressure in people whose high blood pressure isn't controlled by multiple medications. It will involve 50 men and women aged 50-60. Researchers will compare th…

This study is testing if a time-saving workout using whole-body muscle stimulation (WB-EMS) can help lower resting blood pressure and improve other heart health markers. It will involve 42 adults aged 50+ who have mild high blood pressure and are overweight. The goal is to see if…

This study is testing whether time-restricted eating—consuming all daily calories within a 10-hour window—can improve metabolic health in postmenopausal women. Researchers will enroll 164 women aged 45-65 who have prediabetes or metabolic syndrome features. Participants will eith…

This study is testing whether a personalized 12-week lifestyle coaching program can help reverse metabolic syndrome—a cluster of conditions like high blood pressure and high blood sugar that increase heart disease risk. Researchers will compare this intensive program to simple on…

This study is testing whether a dietary supplement called nattokinase, an enzyme from fermented soybeans, can improve several health areas in people at risk for metabolic syndrome who also have sleep problems. Researchers will give about 80 participants either the supplement or a…

This study aims to find out which weight loss method—medication, surgery, or a very strict diet—works best to improve health and potentially extend life for people with metabolic syndrome. It will compare these three approaches in 150 adults over 24 weeks, measuring weight loss, …

This study aims to understand how tiny air pollution particles and noise affect heart and metabolic health in middle-aged city residents. It will also test if simple lifestyle changes, like daily walks in green spaces or following a Mediterranean diet, can help lower these health…

This study is looking at whether treating a common stomach infection (H. pylori) can help improve related health issues like high blood sugar and cholesterol. Researchers will also test if adding probiotics or a natural supplement (berberine) to the standard treatment makes these…

This study is testing a community-based program that pairs a health coach with a smartphone app to help people with metabolic syndrome make lasting lifestyle changes. The program focuses on improving diet, exercise, and emotional well-being to better control weight and reduce the…

This study aims to create a new, non-invasive way to diagnose metabolic health issues by analyzing a person's exhaled breath. Researchers will use a special machine to measure chemicals in the breath of 300 people, including those with metabolic syndrome, those who are obese but …

This study is testing whether eating special food formulations daily can improve health in people at risk of developing metabolic syndrome. Forty adults who don't yet have the condition but have some risk factors like higher waist size or borderline blood sugar will eat foods con…

This large study is testing a new way to prevent heart attacks and strokes in people at risk. It compares two approaches: the standard method based on risk factors like age and diabetes versus a personalized method that uses a special heart scan to see actual artery plaque. The g…

This study is testing whether a program that teaches racial justice activism can prevent depression and improve physical health in Black and Latinx teenagers and young adults. Researchers will enroll 300 participants aged 15-20 in Chicago. Half will receive activism training, whi…

This study explores whether virtual reality (VR) experiences that simulate exercise can produce health benefits similar to actual physical activity in sedentary adults with prediabetes. Researchers will measure changes in blood sugar control, walking endurance, and other metaboli…

This study is testing a new, safe imaging technology to look at 'brown fat,' a type of fat that burns calories for heat. Researchers want to see if this scan can measure how brown fat works and spot differences between healthy people and those with metabolic syndrome. Participant…

This study aims to understand if having a persistent H. pylori stomach infection makes insulin resistance worse in people with metabolic syndrome. Researchers will compare 100 participants, split into groups with and without the infection, by looking at their blood sugar, inflamm…

This study aims to understand how physical activity and inactivity affect the body as we age. Researchers will ask 40 adults aged 50-65 to either increase their activity to recommended levels or decrease it to a typical sedentary level for six months. They will measure changes in…

This study aims to track the long-term health of over 4,000 Shanghai adults to understand how heart, kidney, and metabolic conditions develop and interact over time. Researchers will follow the same group of people originally examined in 2016-2017, checking their health periodica…

This study aims to understand how Polycystic Ovary Syndrome (PCOS) affects heart and blood vessel health. Researchers will measure specific markers of heart and blood vessel function in 120 women with PCOS before and after a sugar test, and again six months after starting a treat…

This study aims to understand how drinking a single glass of red or white wine might affect tiny particles in the blood called extracellular vesicles, which carry signals between cells. Researchers will enroll 8 healthy adults to drink wine and have their blood tested before and …

This study aims to understand and develop new ways to test the function of the choroid plexus, a critical brain barrier. Researchers will study 65 participants, including people with a rare condition called LHIPFOLD, other neurological patients, and healthy volunteers. They will …

This study aims to follow 2000 adults with metabolic syndrome or prediabetes over time to understand how these conditions progress. Researchers will collect health data to identify which factors most influence the development of serious complications like heart disease and diabet…

This 5-year study follows 1500 Polish twins to understand how metabolic syndrome develops and leads to various health problems like liver disease, diabetes, and heart conditions. Researchers will track participants' health over time to identify risk factors and see how genetics a…

This study aims to understand how a person's genes affect how their immune cells respond to potential threats. Researchers will collect blood from healthy volunteers to grow immune cells in a lab and test their reactions. The goal is to learn if certain genetic patterns make peop…

This study is trying to find out if a simple blood test for a protein called BNP, taken when a baby is just one month old, can help predict which teenagers are at risk for developing metabolic syndrome. Metabolic syndrome is a group of conditions like high blood pressure and high…

This study aims to understand how obesity and aging affect the body's metabolism, which could lead to better health in later life. Researchers will observe 650 young and older adults, some with and some without obesity, to find biological signs of aging in the blood. The goal is …

The purpose of this study is to determine 1) if young adults with metabolic syndrome display endothelial dysfunction of the internal carotid artery in a sex-specific fashion and 2) if this endothelial dysfunction can be acutely improved with a single bout of exercise. This will b…