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Scientists probe immune System's role in chronic disease

NCT ID NCT01143480

First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 33 times

Summary

This study looks at how the body's innate immune system responds to certain environmental exposures by measuring inflammation markers in blood. Researchers will collect blood samples from up to 725 healthy volunteers aged 18-45 to analyze how specific genes and proteins react. The goal is to better understand how these responses might contribute to chronic illnesses like asthma, atherosclerosis, and cancer.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • NIEHS Clinical Research Unit (CRU)

    RECRUITING

    Research Triangle Park, North Carolina, 27709, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could help explain how environmental factors trigger inflammation that may lead to chronic diseases.

What could go wrong

This is an observational study in healthy volunteers, not a treatment trial. It may not directly lead to new therapies or apply to people with existing conditions.

Conditions

The condition(s) this trial relates to.

abdominal obesity-metabolic syndrome asthma atherosclerosis cancer Insulin Resistance metabolic syndrome X neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.