Chang Gung Memorial Hospital

This study is testing whether combining two types of drugs works better than one to slow cognitive decline in early Alzheimer's disease or mild cognitive impairment. Researchers will give 80 participants a drug that affects brain signaling (an NMDA-enhancing agent) plus an antiox…

This study is testing whether adding a medication called Kremezin (AST-120) to standard care helps people recover from acute kidney injury. Researchers want to see if the drug can lower harmful toxins in the blood, help the kidneys heal better, and prevent the injury from turning…

This study is testing if adding a precise form of radiation (proton therapy) to a standard two-drug treatment can better control advanced liver cancer that cannot be removed by surgery. It will involve 45 patients to see if the combination is safe, slows cancer growth, and boosts…

This study is testing whether an injection made from donated amniotic fluid can reduce pain and improve function in people with knee osteoarthritis. Researchers will compare this new injection against two others: a standard hyaluronic acid injection and a simple saline (saltwater…

This study is testing if starting two cholesterol-lowering drugs together works better than one alone for people who recently had a stroke. The goal is to quickly get 'bad' cholesterol to a very low level to help prevent another stroke. About 300 patients in Taiwan who had a stro…

This early-stage study is testing whether transferring healthy gut bacteria from a donor (a fecal microbiota transplant) can improve both gastrointestinal problems and core autism symptoms. It will involve 60 participants aged 7-30 with autism and gut issues. Researchers aim to s…

This study is testing whether combining precise proton radiation therapy with two immunotherapy drugs can better control advanced liver cancer that cannot be surgically removed. The trial will enroll 45 patients to see if this combination is safe and more effective than current s…

This early-stage trial is testing the safety and initial effectiveness of a new drug, HCB101, when added to standard chemotherapy for advanced colorectal cancer. It will involve about 40 adults whose cancer has worsened after first-line treatment. The main goals are to find a saf…

This study is testing whether an experimental drug called DAOIB can help slow cognitive decline in people with early Alzheimer's disease or mild memory problems. Researchers will give DAOIB to 123 participants for 24 weeks and track their memory, thinking skills, and daily functi…

This study is testing a new, personalized treatment plan for people with oral cancer who have a high risk of the cancer returning. After initial surgery and radiation/chemotherapy, a blood test will check for leftover cancer cells. If the test is positive, patients will receive l…

This study is testing if adding a new immunotherapy drug, dostarlimab, to the standard treatment of chemotherapy and radiation works better for a rare and aggressive type of cervical cancer. It aims to see if this combination helps patients live longer without their cancer gettin…

This study aims to find the best surgical method for repairing a torn ACL (anterior cruciate ligament) in the knee. Researchers will compare two different surgical techniques that both include an extra ligament repair to improve stability. They will measure which method helps pat…

This study is testing a new AI chatbot program designed to improve communication between nursing home staff and residents' families. Researchers want to see if better communication helps ease depression and improve daily living for residents, while also supporting the mental heal…

This study is testing if a drug called DAOIB can help improve thinking, memory, and mood problems in people with long COVID. All 40 participants will take DAOIB for 24 weeks and have their symptoms checked regularly. The goal is to see if the treatment can ease the cognitive symp…

This study is testing whether adding laser acupuncture to standard diet and exercise advice helps overweight menopausal women lose weight and improve their body shape. Researchers will compare 40 women who receive the laser treatment to those who only get lifestyle guidance. The …

This study is testing if a special cushion (DaSuit®) can help reduce discomfort from sitting and improve posture in adults with low back pain. Researchers will compare it to a look-alike placebo cushion. Participants will sit on each cushion for short sessions while their sitting…

This study is testing whether a modern, painless form of acupuncture using low-level laser light can help reduce shoulder pain and improve movement in people recovering from a stroke. It will involve 58 adults who have had a stroke and are experiencing shoulder pain. Researchers …

This study is testing a new rehabilitation program for people who have had a stroke. It combines robot-assisted arm training with practical task practice in a rotating 'circuit' format. The goal is to see if this approach can improve arm movement, daily function, and overall qual…

This study is testing new virtual and mixed reality systems designed to help people recover arm and hand function after a stroke. It compares these high-tech mirror therapy methods to the traditional version to see which is better at improving movement and daily independence. The…

This study is testing whether specially designed online interactive videos can help people who have had surgery for rectal cancer. It aims to see if these videos can improve common post-surgery bowel problems (known as LARS), reduce psychological distress, and boost overall quali…

This study is testing if watching a short educational video before cataract surgery can help patients feel less anxious and better understand their own care. About 118 patients will be randomly assigned to either watch the video or receive standard instructions. Researchers will …

This study aims to see if a simple blood test, called a liquid biopsy, can predict how well patients with head and neck cancer will respond to immunotherapy. Researchers will compare results from the blood test to traditional tissue biopsies and track how patients' cancers respon…

This study is testing a new 20-hour training course for people who care for the elderly, focusing on how to safely feed patients who have trouble chewing or swallowing. It will enroll 150 student and professional care workers to see if the course improves their knowledge and skil…

This study aims to understand how muscle fatigue affects balance and walking, and whether these effects differ between older and younger adults. Researchers will recruit 140 healthy participants, split into a younger group (20-40 years) and an older group (60-85 years). Participa…

This study aims to learn how certain markers in the blood change when cancer patients receive immunotherapy. Researchers will collect blood samples from 300 participants before and after their treatment to measure these markers. The goal is to gather knowledge that could help und…

This study aims to understand if different types of lasers used in cataract and vision correction surgery affect how quickly and well the eye heals. Researchers will measure signs of inflammation and stress in the eye fluid and tears of 1,000 patients after surgery. The goal is t…

This large research study aims to understand why some people develop serious health problems related to metabolic syndrome, like heart disease and fatty liver. Researchers will collect blood, urine, and stool samples from over 6,000 participants, both with and without metabolic s…

This study aims to understand why cancer patients are at much higher risk of developing dangerous blood clots. Researchers will examine blood clots removed from 120 participants, some with cancer and some without, to compare their contents. The goal is to learn how cancer cells m…