Could amniotic fluid injections ease knee arthritis pain?

NCT ID NCT06704893

Recruiting now Disease control Sponsor: Chang Gung Memorial Hospital Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This Phase 3 trial tests whether injections of amniotic suspension allograft (ASA) can reduce pain and improve function in people with knee osteoarthritis. 160 participants will receive either ASA, hyaluronic acid, or a saline placebo. Researchers will track pain, knee function, and quality of life for one year.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: amniotic suspension allograft (ASA) injection
What this could lead to: If it works, this could offer a new non-surgical option to reduce knee pain and improve function in people with osteoarthritis.
What could go wrong: This is an early Phase 3 trial with only 160 participants. The treatment may not prove better than existing options like hyaluronic acid, and long-term safety is still being studied.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

osteoarthritis osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

KNEE OSTEOARTHRITIS

Contacts and locations

Locations

Department of Physical Medicine and Rehabilitation, Kaohsiung Chang Gung Memorial Hospital
RECRUITING

Kaohsiung City, 833, Taiwan
Kaohsiung Chang Gung Memorial Hospital
RECRUITING

Kaohsiung, Taiwan, 833, Taiwan

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