New combo therapy aims to boost liver cancer survival

NCT ID NCT06999694

First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This phase 2 trial tests a new combination treatment for people with advanced liver cancer that cannot be removed by surgery. It combines precise proton radiation with two immunotherapy drugs, tremelimumab and durvalumab. The goal is to see if this approach is safe and works better than current treatments. About 45 participants will be enrolled.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Proton radiotherapy, tremelimumab, and durvalumab

What this could lead to

If successful, this combination could offer a more effective treatment option for advanced liver cancer, potentially improving survival and tumor control.

What could go wrong

This is an early phase 2 trial with only 45 participants, so results may not apply to everyone. Side effects from the drugs and radiation can be serious.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

hepatocellular carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Chang Gung Memorial Hospital at Linkou

    RECRUITING

    Taoyuan City, Taiwan, 333, Taiwan

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••