Metabolic MRI may reveal hidden cancer responses and spare patients from surgery
NCT ID NCT07730541
First seen Jul 28, 2026 · Last updated Jul 29, 2026 · Updated 1 time
Summary
This trial tests whether a new type of MRI, called hyperpolarized carbon-13 MRI, can better predict how rectal cancer responds to chemoradiotherapy. By tracking how cancer cells use energy, along with blood and tissue analysis, researchers hope to identify complete tumor responses that standard scans might miss. The study involves 30 adults with rectal cancer who will undergo imaging before and after treatment. If the approach works, it could help doctors decide who can safely avoid surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- hyperpolarized [1-13C]pyruvate injection for metabolic MRI
- What this could lead to
- If successful, this imaging approach could help doctors predict which rectal cancer patients respond completely to chemoradiotherapy, potentially sparing them from unnecessary surgery.
- What could go wrong
- This is a small, early-phase study with only 30 participants, so results may not apply to all patients. The technique is complex and not yet widely available.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Chang Gung Memorial hospital
RECRUITINGTaoyuan, 333, Taiwan
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- A new radiation combo may spare the rectum in early cancer
- Can a triple-drug cocktail after short radiation eliminate rectal cancer without surgery?
- Can a beetroot drink spot dangerous surgical leaks before they turn deadly?
- Rearranging the treatment timeline: could a new sequence of chemo and radiation spare rectal cancer patients from major surgery?