Immunotherapy plus chemo shows promise for rare cervical cancer

NCT ID NCT07336147

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study is testing whether adding the immunotherapy drug dostarlimab to standard chemotherapy and radiation can help women with a rare and aggressive type of cervical cancer called small cell neuroendocrine carcinoma. About 45 women with early to advanced stages of the disease will receive the combination treatment. The goal is to see if this approach improves how long women live without their cancer getting worse, compared to past results with standard treatment alone.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Dostarlimab (an immunotherapy drug) combined with cisplatin and etoposide (chemotherapy) and radiotherapy
What this could lead to
If successful, this could offer a more effective treatment option for a rare and aggressive cervical cancer, potentially improving survival rates.
What could go wrong
This is a small Phase 2 trial with only 45 participants, so results may not apply to all patients. The combination therapy may cause significant side effects, and the improvement in survival is not guaranteed.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Chang Gung Memorial Hospital, Linkou Branch

    RECRUITING

    Taoyuan, Taiwan, 333, Taiwan

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Other studies related to the condition(s) this trial covers.