New combo pill could slash stroke risk by crushing cholesterol
NCT ID NCT07307989
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether combining a statin with ezetimibe (another cholesterol-lowering drug) works better than a statin alone in people who recently had a stroke. Researchers will enroll 300 adults aged 20 or older who had a stroke or TIA within the past 30 days and have high LDL cholesterol. Participants will be randomly assigned to one of two groups and followed to see if the combo helps more people reach a target LDL level below 70 mg/dL.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
statin plus ezetimibe
What this could lead to
If successful, this could show that a simple two-drug combination is more effective than a statin alone at lowering cholesterol after a stroke, potentially reducing the risk of future strokes.
What could go wrong
This is a phase 2 trial with 300 participants, so results are still early. The combination may not prove significantly better, and some patients may experience side effects like muscle pain or digestive issues.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Chang Gung Memorial Hospital, Chiayi Branch
RECRUITINGPozi, 613, Taiwan
Contact Phone: •••-•••-•••• Email: •••••@•••••