New drug DAOIB hopes to clear long COVID brain fog
NCT ID NCT05764538
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a drug called DAOIB in 40 people with Long COVID who have memory and thinking problems (brain fog). Everyone gets the drug for 24 weeks, and researchers check their thinking skills, mood, and quality of life every 8 weeks. The goal is to see if DAOIB can help improve cognitive function.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- DAOIB (a drug)
- What this could lead to
- If it works, this could point toward a treatment for brain fog and other cognitive problems caused by Long COVID.
- What could go wrong
- This is a small, early-phase trial with only 40 people and no placebo group, so results may not be reliable. The drug may not work or could have side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Kaohsiung Chang Gung Memorial Hospital
RECRUITINGKaohsiung City, 886, Taiwan
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Five years on: how does long COVID evolve?
- Could exercise retrain the heart in long COVID?
- Can brain games and gentle currents lift long COVID brain fog?
- Can brain training zap long COVID brain fog?
- Ear device zaps vagus nerve in bid to quiet long COVID fatigue and brain fog
- Smartphone therapy could ease long COVID's mental toll