New combo therapy aims to boost immune attack on liver tumors

NCT ID NCT06133062

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 2 trial is testing whether adding proton radiotherapy to standard immunotherapy (atezolizumab and bevacizumab) can better control advanced liver cancer that cannot be removed by surgery. About 45 participants will receive the combination treatment. The study will measure how long the cancer stays under control and monitor side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

atezolizumab and bevacizumab (immunotherapy and anti-angiogenic drugs) plus proton radiotherapy

What this could lead to

If successful, this combination could improve tumor control and survival for people with advanced liver cancer that cannot be surgically removed.

What could go wrong

This is a small, early-phase trial (45 participants) without a comparison group, so results may not be definitive. Side effects from the drugs and radiation are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

hepatocellular carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Chang Gung Memorial Hospital at Linkou

    RECRUITING

    Taoyuan City, Taiwan, 333, Taiwan

    Contact Phone: •••-•••-•••• Email: •••••@•••••