Could a simple diet change save ICU patients with high phenylalanine?

This study tests whether a phenylalanine-free diet, similar to that used for a rare genetic condition, can safely lower high blood phenylalanine levels in critically ill adults in the ICU. High phenylalanine in these patients is linked to a higher risk of death and brain problems. The trial will enroll 100 adults with severe illness and high phenylalanine levels to see if this dietary approach improves outcomes.