Intestinal disorder
MONDO:0005020A non-neoplastic or neoplastic disorder that affects the small or large intestine.
Also known as: disease of intestine, disease or disorder of intestine, disorder of intestine, intestinal disease, intestinal disorder, intestine disease, intestine disease or disorder, disease, intestinal
5443 clinical trials for this condition and its sub-types, 70 tagged with Intestinal disorder itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Intestinal disorder
-
Large intestine disorder 2 trials · 3,821 incl. sub-types
11 sub-types
- Colorectal neoplasm 1,495 trials · 2,900 incl. sub-types Sub-types →
- Colonic disorder 18 trials · 1,470 incl. sub-types Sub-types →
- Rectal disorder 22 trials · 793 incl. sub-types Sub-types →
- Disorder of appendix 1 trial · 132 incl. sub-types Sub-types →
- Polyp of large intestine 60 trials · 114 incl. sub-types Sub-types →
- Anal canal cancer 22 trials · 44 incl. sub-types Sub-types →
- Epithelial tumor of anal canal 0 trials · 34 incl. sub-types Sub-types →
- Shigellosis 14 trials
- Crohn's colitis 7 trials
- Benign neoplasm of large intestine 4 trials · 6 incl. sub-types Sub-types →
- Colorectal Kaposi sarcoma 0 trials Sub-types →
-
Intestinal neoplasm 4 trials · 3,080 incl. sub-types
6 sub-types
- Colorectal neoplasm 1,495 trials · 2,900 incl. sub-types Sub-types →
- Intestinal cancer 25 trials · 2,791 incl. sub-types Sub-types →
- Small intestine neoplasm 1 trial · 223 incl. sub-types Sub-types →
- Epithelial tumor of anal canal 0 trials · 34 incl. sub-types Sub-types →
- Intestinal neuroendocrine neoplasm 7 trials · 21 incl. sub-types Sub-types →
- Intestinal benign neoplasm 1 trial · 7 incl. sub-types Sub-types →
-
Inflammatory bowel disease 430 trials · 1,081 incl. sub-types
40 sub-types
- Colitis 41 trials · 679 incl. sub-types Sub-types →
- Crohn disease 563 trials · 569 incl. sub-types Sub-types →
- Proctitis 2 trials · 21 incl. sub-types Sub-types →
- Inflammatory bowel disease 1 3 trials
- Undetermined colitis 3 trials
- Ulcerative proctosigmoiditis 2 trials
- ALPI-related inflammatory bowel disease 0 trials
- IL10-related early-onset inflammatory bowel disease 0 trials Sub-types →
- TRIM22-related inflammatory bowel disease 0 trials
- Cap polyposis 0 trials
- Cutaneous photosensitivity-lethal colitis syndrome 0 trials
- Inflammatory bowel disease (infantile ulcerative colitis) 31, autosomal recessive 0 trials
- Inflammatory bowel disease 10 0 trials
- Inflammatory bowel disease 11 0 trials
- Inflammatory bowel disease 12 0 trials
- Inflammatory bowel disease 13 0 trials
- Inflammatory bowel disease 14 0 trials
- Inflammatory bowel disease 15 0 trials
- Inflammatory bowel disease 16 0 trials
- Inflammatory bowel disease 17 0 trials
- Inflammatory bowel disease 18 0 trials
- Inflammatory bowel disease 19 0 trials
- Inflammatory bowel disease 2 0 trials
- Inflammatory bowel disease 20 0 trials
- Inflammatory bowel disease 21 0 trials
- Inflammatory bowel disease 22 0 trials
- Inflammatory bowel disease 23 0 trials
- Inflammatory bowel disease 24 0 trials
- Inflammatory bowel disease 26 0 trials
- Inflammatory bowel disease 27 0 trials
- Inflammatory bowel disease 29 0 trials
- Inflammatory bowel disease 3 0 trials
- Inflammatory bowel disease 30 0 trials
- Inflammatory bowel disease 4 0 trials
- Inflammatory bowel disease 5 0 trials
- Inflammatory bowel disease 6 0 trials
- Inflammatory bowel disease 7 0 trials
- Inflammatory bowel disease 8 0 trials
- Inflammatory bowel disease 9 0 trials
- Neonatal inflammatory skin and bowel disease 0 trials Sub-types →
-
Gastroenteritis 20 trials · 839 incl. sub-types
9 sub-types
- Colitis 41 trials · 679 incl. sub-types Sub-types →
- Appendicitis 76 trials
- Intestinal infectious disease 3 trials · 49 incl. sub-types Sub-types →
- Inflammatory diarrhea 0 trials · 33 incl. sub-types Sub-types →
- Enteritis 5 trials · 23 incl. sub-types Sub-types →
- Eosinophilic gastroenteritis 6 trials · 7 incl. sub-types Sub-types →
- Campylobacteriosis 3 trials Sub-types →
- Intestinal tuberculosis 2 trials
- Salmonella gastroenteritis 0 trials
-
Small intestine disorder 7 trials · 387 incl. sub-types
10 sub-types
- Small intestine neoplasm 1 trial · 223 incl. sub-types Sub-types →
- Duodenal disorder 1 trial · 109 incl. sub-types Sub-types →
- Celiac disease 81 trials Sub-types →
- Enteritis 5 trials · 23 incl. sub-types Sub-types →
- Pouchitis 18 trials
- Small intestinal bacterial overgrowth 18 trials
- Atresia of small intestine 0 trials
- Congenital short bowel syndrome 0 trials Sub-types →
- Small intestine diverticulitis 0 trials Sub-types →
- Small intestine duplication 0 trials Sub-types →
-
Irritable bowel syndrome 223 trials
-
Bowel dysfunction 11 trials · 211 incl. sub-types
1 sub-type
- Constipation disorder 189 trials · 202 incl. sub-types Sub-types →
-
Glucose-galactose malabsorption 2 trials · 151 incl. sub-types
1 sub-type
- Glucose intolerance 149 trials
-
Malabsorption syndrome 13 trials · 120 incl. sub-types
9 sub-types
- Celiac disease 81 trials Sub-types →
- Autoimmune enteropathy 2 trials · 11 incl. sub-types Sub-types →
- Lactose intolerance 9 trials · 10 incl. sub-types Sub-types →
- Idiopathic malabsorption due to bile acid synthesis defects 4 trials
- Intestinal disaccharidase deficiency 0 trials · 2 incl. sub-types Sub-types →
- Blind loop syndrome 1 trial
- Tropical sprue 1 trial
- Hereditary folate malabsorption 0 trials
- Lysine malabsorption syndrome 0 trials
-
Intestinal obstruction 44 trials · 91 incl. sub-types
6 sub-types
- Ileus 10 trials · 42 incl. sub-types Sub-types →
- Intestinal volvulus 4 trials
- Duodenal obstruction 2 trials · 3 incl. sub-types Sub-types →
- Encapsulating peritoneal sclerosis 2 trials
- Intussusception 2 trials
- Intestinal impaction 0 trials
-
Eosinophilic gastrointestinal disease 9 trials · 73 incl. sub-types
3 sub-types
- Eosinophilic esophagitis 67 trials Sub-types →
- Eosinophilic gastroenteritis 6 trials · 7 incl. sub-types Sub-types →
- Proton-pump inhibitor-responsive esophageal eosinophilia 0 trials
-
Intestinal fistula 6 trials · 63 incl. sub-types
1 sub-type
- Anal fistula 57 trials
-
Necrotizing enterocolitis 51 trials
1 sub-type
- Perinatal necrotizing enterocolitis 9 trials
-
Short bowel syndrome 39 trials
1 sub-type
- Secondary short bowel syndrome 0 trials
-
Intestinal motility disease 10 trials · 39 incl. sub-types
15 sub-types
- Hirschsprung disease 29 trials
- Multisystemic smooth muscle dysfunction syndrome 2 trials Sub-types →
- Goldberg-Shprintzen syndrome 0 trials
- Haddad syndrome 0 trials
- Hirschsprung disease-ganglioneuroblastoma syndrome 0 trials
- Hirschsprung disease-hearing loss-polydactyly syndrome 0 trials
- Hirschsprung disease-nail hypoplasia-dysmorphism syndrome 0 trials
- Hirschsprung disease-type D brachydactyly syndrome 0 trials
- Waardenburg-Shah syndrome 0 trials Sub-types →
- Chronic intestinal pseudoobstruction 0 trials Sub-types →
- Congenital diarrhea 6 0 trials
- Familial visceral myopathy 0 trials Sub-types →
- Intestinal obstruction in the newborn due to guanylate cyclase 2C deficiency 0 trials
- Megacystis-microcolon-intestinal hypoperistalsis syndrome 0 trials Sub-types →
- Oculogastrointestinal muscular dystrophy 0 trials
-
Diverticulitis 28 trials · 34 incl. sub-types
2 sub-types
- Diverticulitis of colon 19 trials
- Small intestine diverticulitis 0 trials Sub-types →
-
Chronic intestinal failure 24 trials
-
Neurogenic bowel 22 trials
-
Postgastrectomy syndrome 2 trials · 20 incl. sub-types
2 sub-types
- Dumping syndrome 19 trials
- Afferent loop syndrome 0 trials
-
Hypertrophic pyloric stenosis 16 trials
2 sub-types
-
Parasitic intestinal disorder 0 trials · 16 incl. sub-types
7 sub-types
- Intestinal helminthiasis 3 trials · 9 incl. sub-types Sub-types →
- Cryptosporidiosis 5 trials
- Giardiasis 2 trials
- Protozoal dysentery 0 trials · 1 incl. sub-types Sub-types →
- Blastocystis infectious disease 0 trials
- Balantidiasis 0 trials
- Dientamoebiasis 0 trials
-
Ischemic bowel disorder 8 trials · 15 incl. sub-types
1 sub-type
- Acute intestinal ischemia 12 trials
-
Endometriosis of intestine 9 trials
-
Intestinal perforation 9 trials
2 sub-types
- Perinatal intestinal perforation 0 trials
- Spontaneous intestinal perforation 0 trials
-
Intestinal polyp 8 trials
-
Protein-losing enteropathy 7 trials
-
Intestinal atresia 3 trials · 6 incl. sub-types
2 sub-types
- Duodenal atresia 2 trials
- Multiple intestinal atresia 0 trials · 1 incl. sub-types Sub-types →
-
Refractory celiac disease 4 trials
-
Volvulus of midgut 4 trials
1 sub-type
-
Abetalipoproteinemia 2 trials
-
Pneumatosis cystoides intestinalis 2 trials
-
Angiodysplasia of intestine 1 trial
-
Steatorrhea 1 trial
1 sub-type
- Pancreatic steatorrhea 0 trials
-
4-hydroxyphenylacetic aciduria 0 trials
-
NK-cell enteropathy 0 trials
-
Satoyoshi syndrome 0 trials
-
Whipple disease 0 trials
-
Collagenous sprue 0 trials
-
Intestinal dysmotility syndrome 0 trials
-
Intestinal lymphangiectasia 0 trials
2 sub-types
- Primary intestinal lymphangiectasia 0 trials
- Secondary intestinal lymphangiectasia 0 trials
-
Isolated mesenteric vein thrombosis 0 trials
-
Malakoplakia 0 trials
-
Mucocele of appendix 0 trials
-
Primary desmosis coli 0 trials
-
Solitary rectal ulcer syndrome 0 trials
-
Trichohepatoenteric syndrome 0 trials
2 sub-types
- Trichohepatoenteric syndrome 1 0 trials
- Trichohepatoenteric syndrome 2 0 trials
Most studied deeper sub-types
-
Timing of stoma reversal could cut hospital stays
Disease control CompletedThis trial compares two timings for closing a temporary ileostomy after bowel surgery: early (within 8 weeks) versus delayed (after 8 weeks). The goal is to see which approach leads to a shorter post-operative hospital stay. Adults aged 18-65 with a temporary ileostomy scheduled …
Sponsor: Dr. Waseem Ullah • Aim: Disease control
Last updated Aug 28, 2026 00:00 UTC
-
Can a glass of pomegranate juice tame gut inflammation?
Disease control CompletedThis trial investigates whether drinking pomegranate juice for 12 weeks can reduce gut inflammation in people with Crohn's disease or ulcerative colitis who are in remission. Participants will drink either pomegranate juice or a placebo beverage twice daily, and researchers will …
Sponsor: IRCCS Azienda Ospedaliero-Universitaria di Bologna • Aim: Disease control
Last updated Aug 02, 2026 00:00 UTC
-
Drain or no drain? landmark trial settles debate after rectal cancer surgery
Disease control CompletedThis study tested whether placing a temporary drain in the pelvis after rectal cancer surgery reduces the risk of serious infections like leaks or abscesses. About 500 patients were randomly assigned to receive a drain or not. The main goal was to see if drainage lowered pelvic s…
Phase 3 • Sponsor: University Hospital, Bordeaux • Aim: Disease control
Last updated Jun 27, 2026 12:34 UTC
-
Could a daily sachet ease your IBS? new trial tests skal pro
Symptom relief CompletedThis study tests whether a daily dose of Skal Pro—a mix of a friendly bacteria (Lactobacillus plantarum 299v) and a prebiotic fiber—can reduce IBS symptoms like belly pain, bloating, and irregular bowel movements. Sixty adults with IBS will receive either the supplement or a dumm…
Phase 4 • Sponsor: EP Plus Group Sdn Bhd • Aim: Symptom relief
Last updated Sep 13, 2026 00:00 UTC
-
Which drug gets your gut moving faster after bowel surgery?
Symptom relief CompletedThis study compares two medications used to reverse muscle relaxants after bowel surgery: Sugammadex versus Neostigmine with Glycopyrrolate. The goal is to see which one helps patients have their first bowel movement and tolerate solid food sooner. About 128 adults undergoing lap…
Phase 4 • Sponsor: University of California, Irvine • Aim: Symptom relief
Last updated Aug 27, 2026 00:00 UTC
-
Morning espresso may Kick-Start digestion after pancreatic surgery
Symptom relief CompletedThis trial investigates whether drinking coffee after pancreatic surgery can help the bowel start working again sooner. About 200 adults who had open pancreatic surgery will receive either regular coffee, decaf coffee, or water twice a day. The main goal is to see how quickly the…
Sponsor: Azienda Ospedaliera Universitaria Integrata Verona • Aim: Symptom relief
Last updated Jun 27, 2026 13:05 UTC
-
Toilet posture hack eases bathroom struggles for rectocele patients
Symptom relief CompletedThis study looked at whether using a special footstool to change your sitting posture on the toilet can make bowel movements easier for people with a rectocele (a type of pelvic organ prolapse). Sixty participants tried the device and rated their straining on a 0-10 scale. The go…
Sponsor: TriHealth Inc. • Aim: Symptom relief
Last updated Jun 27, 2026 09:00 UTC
-
New device helps kids with bowel problems – study shows promise
Symptom relief CompletedThis study tested a new, smaller bowel irrigation device called Navina Mini in 27 children and teens aged 3 to 17 with bowel problems like severe constipation or leakage. The goal was to see if the device is safe, easy to use, and improves bowel emptying and satisfaction. Results…
Sponsor: Wellspect HealthCare • Aim: Symptom relief
Last updated Jun 27, 2026 07:51 UTC
-
Early palliative care may boost quality of life in advanced GI cancers
Symptom relief CompletedThis study looked at whether early contact with a palliative care unit improves quality of life for people with advanced cancers of the upper gastrointestinal tract or colorectal cancer. 108 participants were randomly assigned to either early palliative care or standard care (con…
Sponsor: Lund University Hospital • Aim: Symptom relief
Last updated Jun 26, 2026 16:42 UTC
-
Hidden gut inflammation may drive familial mediterranean fever
Knowledge-focused CompletedResearchers are studying whether the lining of the small intestine shows signs of inflammation in people with Familial Mediterranean Fever (FMF), a genetic condition that causes recurring fevers and pain. The study compares intestinal biopsy samples from about 30 adults with FMF …
Sponsor: Hitit University • Aim: Knowledge-focused
Last updated Sep 17, 2026 00:00 UTC
-
Gluten: friend or foe for elite athletes?
Knowledge-focused CompletedThis trial investigates whether gluten consumption affects digestive comfort, quality of life, and physical performance in non-celiac athletes who train intensively. Participants, who are healthy and free of digestive diseases, will be randomly assigned to a gluten-containing or …
Sponsor: University Hospital, Clermont-Ferrand • Aim: Knowledge-focused
Last updated Aug 08, 2026 00:03 UTC
-
Sugar and stress: could fructose malabsorption fuel anxiety?
Knowledge-focused CompletedThis study looked at whether difficulty digesting fructose (a sugar found in many foods) is linked to anxiety and changes in gut bacteria. Researchers compared 56 healthy young men who either absorb fructose normally or have trouble absorbing it. The goal was to see if fructose m…
Sponsor: University Hospital, Rouen • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:34 UTC
-
App vs. phone: which triage method guides patients better?
Knowledge-focused CompletedThis study tested whether a digital symptom checker could work as well as a traditional phone call for guiding patients to the right level of care. Researchers planned to include 120 adults from a primary care center, but only 22 took part. The main goal was to see if a larger tr…
Sponsor: Region Skane • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
-
Tiny additive could cut risk in abdominal pain blocks
Knowledge-focused CompletedThis study looked at whether adding diluted epinephrine to the numbing drug ropivacaine during a TAP block (a pain block for abdominal surgery) lowers the peak amount of ropivacaine in the blood. Forty adults having laparoscopic colectomy received either ropivacaine alone or with…
Sponsor: Centre Hospitalier Universitaire de Nice • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
-
Which scope spots more gut problems? new study investigates
Knowledge-focused CompletedThis study looked at whether using a forward-viewing scope during a procedure called ERCP helps doctors find more important gut problems than the usual side-viewing scope. 163 adults who needed ERCP had two back-to-back exams with different scopes. The goal was to see how often t…
Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
-
Facemasks tested for safety in endoscopy procedures
Knowledge-focused CompletedThis study looked at whether wearing a special facemask during upper endoscopy (a procedure to examine the stomach and esophagus) can reduce the spread of tiny particles into the air. The goal was to better understand infection risks, like COVID-19, for healthcare workers. Resear…
Sponsor: Anthony Lembo • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
-
Tiny patients, big questions: antibiotic levels in infant bowel surgery
Knowledge-focused CompletedThis study looked at how the antibiotic metronidazole spreads into the intestinal tissue of 21 infants (ages 0-2) during planned bowel surgery. Researchers took blood and tissue samples at several time points to measure drug levels. The goal is to find the best dose to prevent in…
Sponsor: Duke University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC
-
Simple stool test may predict deadly gut disease in preemies
Knowledge-focused CompletedThis study looked at whether a simple stool test could help predict serious gut inflammation in premature babies. Researchers collected stool samples from 122 preterm infants born at 33 weeks or less, testing for a protein called calprotectin. The goal was to see if this test, co…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:21 UTC