Gluten: friend or foe for elite athletes?

NCT ID NCT03101410

First seen Aug 06, 2026 · Last updated Aug 07, 2026 · Updated 1 time

Summary

This trial investigates whether gluten consumption affects digestive comfort, quality of life, and physical performance in non-celiac athletes who train intensively. Participants, who are healthy and free of digestive diseases, will be randomly assigned to a gluten-containing or gluten-free diet. The study measures digestive symptoms, running performance, body composition, and gut microbiota to see if gluten sensitivity plays a role in athletic well-being.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Gluten (dietary intervention) versus gluten-free diet
What this could lead to
If gluten sensitivity is confirmed in athletes, it could lead to dietary strategies that improve digestive comfort and performance in non-celiac, high-intensity exercisers.
What could go wrong
This is a small, early-stage trial, and results may not apply to all athletes. The effects of gluten may be subtle or vary widely among individuals, and the study may not detect significant differences.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHU Clermont-Ferrand

    Clermont-Ferrand, 63003, France

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