Diverticulitis

This early study is testing whether giving a transplant of healthy gut bacteria (called IMT) through a feeding tube is safe and doable in 40 adults who have had part of their colon removed due to diverticulitis or sigmoid colon cancer. Participants get the transplant a couple of …

This early-stage trial is testing whether a pill made from freeze-dried healthy donor stool (MTP-101P) is safe and can restore good bacteria in people having part of their colon removed. Forty adults aged 18-75 with colon polyps, early-stage cancer, or diverticulitis will take th…

This study looks at whether having surgery soon after a severe diverticulitis attack (within 7-10 days) leads to better quality of life than waiting 6-8 weeks. About 136 patients with complicated or recurrent diverticulitis will be randomly assigned to one of the two timing group…

This trial is developing an AI-powered device that listens to children's heart, breath, and bowel sounds to identify signs of common diseases like congenital heart disease, bronchopneumonia, and abdominal issues. It will involve 30,000 children aged 0-18, some with these conditio…

This study explores whether measuring heart rate variability—the natural ups and downs in heartbeat timing—can help detect complications like leaks or abscesses after planned colorectal surgery. Researchers will monitor patients for a week after surgery and compare heart rate pat…

This study is testing a new blood test that looks at RNA (genetic material) to quickly tell if a person with belly pain has an infection inside the abdomen, like appendicitis or diverticulitis. About 1,000 adults and children over age 7 with abdominal pain will give a blood sampl…

This study looks at whether antibiotics are truly needed for mild diverticulitis. About 100 adults with left-sided diverticulitis will take either two antibiotics or a placebo daily for 10 days, along with standard pain relief and diet changes. The main goal is to see if a larger…

This study is comparing two approaches for people with recurrent, uncomplicated diverticulitis: elective surgery to remove part of the colon versus conservative (non-surgical) management. The goal is to see which approach leads to better bowel function and quality of life. Resear…

This study will follow 430 adults having colorectal surgery to understand why some develop a leak where the bowel is reconnected. Researchers will look at factors before, during, and after surgery. The goal is to create a way to predict and prevent this serious complication.

This study follows 250 people with chronic diverticular disease to see if elective sigmoidectomy (surgery) improves quality of life compared to conservative care (diet, pain relievers, laxatives). Participants are recruited from a surgical clinic in Denmark. The main outcomes are…

This study is looking at how the placement of the stapler spike during colorectal surgery affects bleeding where the bowel is reconnected. About 102 adults having surgery for colorectal cancer or diverticulitis will take part. Doctors will check for bleeding during and after surg…