Poop pills could protect gut after colon surgery – early trial begins
NCT ID NCT06692179
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This early-stage trial is testing whether a pill made from freeze-dried healthy donor stool (MTP-101P) is safe and can restore good bacteria in people having part of their colon removed. Forty adults aged 18-75 with colon polyps, early-stage cancer, or diverticulitis will take the pill after surgery. Researchers will check if the donor bacteria take hold and improve gut health markers.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
freeze-dried fecal microbiota (MTP-101P)
What this could lead to
If successful, this could pave the way for a simple pill to restore healthy gut bacteria after colon surgery, potentially reducing infections like C. diff.
What could go wrong
This is a very early Phase 1 trial with only 40 people, so safety and effectiveness are not yet proven. The treatment may not work or could cause unexpected side effects.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of Minnesota
RECRUITINGMinneapolis, Minnesota, 55414, United States
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