Diverticulitis
MONDO:0004235An infection that develops in the diverticula of the intestinal tract. Signs and symptoms include abdominal pain, fever, and leukocytosis.
Also known as: digestive tract diverticulum inflammation, inflammation of digestive tract diverticulum
32 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsSub-types
Broader categories
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Could antibiotics alone replace drains for diverticulitis abscesses? new pilot study aims to find out
Disease control Not yet recruitingThis pilot study tests whether antibiotics alone are as effective as antibiotics plus percutaneous drainage for treating diverticulitis with a large abscess (4-8 cm). Fifty adults with stable vital signs and no signs of peritonitis will be randomly assigned to one of two groups. …
Phase: NA • Sponsor: Azienda Sanitaria di Firenze • Aim: Disease control
Last updated Jun 27, 2026 08:12 UTC
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Antibiotics may not be needed for mild diverticulitis, new US trial suggests
Symptom relief Not yet recruitingThis trial tests whether people with mild diverticulitis can be safely treated at home with just pain medicines (ibuprofen and acetaminophen) instead of antibiotics. 556 participants will be randomly assigned to receive either pain medicines alone or pain medicines plus an antibi…
Phase: PHASE4 • Sponsor: Montefiore Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 13:02 UTC
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Gut microbes may hold key to diverticular disease
Knowledge-focused Not yet recruitingThis study investigates whether the bacteria living in the gut influence the development of diverticular disease and acute diverticulitis. Researchers will compare the gut microbiota of people with and without these conditions to identify differences and risk factors. The goal is…
Sponsor: Hospital of Navarra • Aim: Knowledge-focused
Last updated Jul 04, 2026 00:00 UTC
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Could skipping bowel prep before colon surgery be just as safe?
Knowledge-focused Not yet recruitingThis study looks at whether it's safe to skip mechanical bowel preparation (the drink that cleans out your colon) before colon surgery. Currently, the best practice combines that drink with antibiotics to prevent infections. The trial will compare two groups: one getting the drin…
Phase: NA • Sponsor: Mount Sinai Hospital, Canada • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:01 UTC
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New study aims to take the guesswork out of emergency diverticulitis surgery
Knowledge-focused Not yet recruitingThis observational study will collect detailed information from 150 adults undergoing emergency surgery for complicated diverticulitis. Researchers will analyze factors that influence surgeons' decisions to perform either a primary anastomosis (reconnecting the bowel) or a Hartma…
Sponsor: IRCCS San Raffaele Roma • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Massive saudi study aims to improve emergency surgery survival
Knowledge-focused Not yet recruitingThis study will collect data from 10,000 patients across Saudi Arabia who undergo emergency abdominal surgery (laparotomy). Researchers will track complications and deaths within 30 and 90 days after surgery. The goal is to understand current care quality, test international risk…
Sponsor: King Faisal Specialist Hospital & Research Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:07 UTC
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Robots to the rescue: can they handle emergency surgery?
Knowledge-focused Not yet recruitingThis study will test whether robotic surgery can be used for emergency abdominal operations, such as for severe gallbladder infections or bowel blockages. The goal is to see if it's feasible and if it can lower complication rates and shorten hospital stays compared to traditional…
Sponsor: Centre Hospitalier Universitaire de Nice • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC