Could a poop pill help heal after colon surgery?
NCT ID NCT06370884
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early study is testing whether giving a transplant of healthy gut bacteria (called IMT) through a feeding tube is safe and doable in 40 adults who have had part of their colon removed due to diverticulitis or sigmoid colon cancer. Participants get the transplant a couple of days after surgery and are followed for up to 6 months to check for side effects and changes in their gut microbiome. The goal is to see if this approach is safe enough to study further for preventing infections like recurrent C. diff.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
intestinal microbiota transplant (IMT) solution
What this could lead to
If it works, this could point toward a way to restore healthy gut bacteria after colon surgery and reduce complications like recurrent C. diff infection.
What could go wrong
This is a very early Phase 1 pilot study with only 40 people, so it is designed just to test safety and feasibility, not effectiveness. There is a small risk of bowel perforation from the feeding tube, and the transplant may not engraft or provide benefit.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of Minnesota
RECRUITINGMinneapolis, Minnesota, 55414, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••