Drain or no drain? landmark trial settles debate after rectal cancer surgery

NCT ID NCT01269567

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether placing a temporary drain in the pelvis after rectal cancer surgery reduces the risk of serious infections like leaks or abscesses. About 500 patients were randomly assigned to receive a drain or not. The main goal was to see if drainage lowered pelvic sepsis within 30 days after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

pelvic drain (a tube placed during surgery to collect fluid)

What this could lead to

If successful, this could confirm that routine drainage after rectal cancer surgery reduces dangerous pelvic infections, improving recovery.

What could go wrong

This trial is completed, but results may not apply to all patients or hospitals. Drains can cause discomfort or rare complications.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

colorectal neoplasm Digestive System Diseases digestive system disorder digestive system neoplasm Digestive System Neoplasms intestinal cancer intestinal disorder Neoplasms by Site rectal disorder rectum adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • APHP- Saint Joseph

    Paris, 75014, France

  • APHP-Kremlin Bicetre

    Le Kremlin-Bicêtre, 94275, France

  • CH de BEAUVAIS

    Beauvais, 60021, France

  • CHRU Lille

    Lille, 59037, France

  • CHRU de Strasbourg

    Strasbourg, 67000, France

  • CHU Poitiers

    Poitiers, France

  • CHU d'AMIENS

    Amiens, 80054, France

  • Centre Hospitalier Lyon Sud

    Lyon, 69495, France

  • Département de Chirurgie Oncologique - CRLC Val d'Aurelle

    Montpellier, 34298, France

  • Département de Chirurgie Oncologique - Centre Oscar Lambret

    Lille, 59020, France

  • Département de Chirurgie Oncologique - Institut Paoli Calmette

    Marseille, 13009, France

  • Service de Chirurgie Digestive - CHU Charles Nicolle

    Rouen, 76031, France

  • Service de Chirurgie Digestive - CHU de Nantes - Hôtel Dieu

    Nantes, 44093, France

  • Service de Chirurgie Digestive - Hôpital A. Michallon

    La Tronche, 38700, France

  • Service de Chirurgie Digestive - Hôpital Purpan - Pavillon Dieulafoy

    Toulouse, 31059, France

  • Service de Chirurgie Digestive - Hôpital Saint-André - CHU de Bordeaux

    Bordeaux, 33075, France

  • Service de Chirurgie Digestive - Hôpital des Diaconnesses - La Croix Saint-Simon

    Paris, 75020, France

  • Service de Chirurgie Digestive et Générale - Brabois

    Vandœuvre-lès-Nancy, 54511, France

  • Service de Chirurgie Digestive et Viscérale - CHU Timone

    Marseille, 13385, France

  • Service de Chirurgie Générale et Digestive - Hôpital Beaujon

    Clichy, 92110, France

  • Service de Chirurgie Générale et Digestive - Hôpital Saint-Antoine

    Paris, 75012, France

  • Service de Chirurgie Viscérale - CHU Pontchaillou

    Rennes, 35033, France