Neurogenic bowel

This study tests whether a spinal cord stimulator — a device that sends mild electrical pulses to the spinal cord — can help people with long-term bladder and bowel problems after a spinal cord injury. Ten adults with injuries older than 6 months will have the device implanted an…

This pilot study is testing a special capsule that vibrates as it moves through the digestive system. The goal is to see if it is safe and helpful for people with spinal cord injuries who have bowel problems. Only 12 participants will be enrolled to check safety and how well they…

This study tests whether using mild electrical pulses in the rectum can help people with spinal cord injury empty their bowels more quickly. Many with spinal cord injury have slow bowel movements and rely on a finger to stretch the rectum. The trial compares the usual method with…

This study tests whether using mild electrical pulses on the belly muscles during a bowel program can cut down the time it takes. Fifteen adults with chronic spinal cord injury (above T11) will try the device at home and track their bowel routine times, quality of life, and any c…

This study tests whether a non-invasive spinal cord stimulation device can improve autonomic functions like blood pressure, bladder, bowel, and sexual control in people with chronic spinal cord injury. Thirty participants will receive targeted stimulation over several weeks. The …

This study tests whether using a small electrical stimulation device on the skin near the genitals can help people with spinal cord injury control bowel accidents. Twelve participants will use the device at home for 6-8 hours daily over 4 weeks. The goal is to see if this approac…

This study tests whether gentle electrical stimulation of a nerve in the genital area can improve bowel control in people with spinal cord injury. Researchers will measure how the rectum and anus respond to the stimulation using a small balloon. The goal is to see if this non-inv…

This study aims to collect medical data and biological samples (blood, urine, stool, and tissue) from up to 4,000 adults with known or suspected gastrointestinal diseases. Participants receive standard medical care at the NIH, and any extra samples or leftover tissue from procedu…

This study looks at two types of enema programs to see which one helps children and adults with spina bifida control their bowel movements better. Participants will fill out online surveys three times over a year. The goal is to find out which method prevents accidents, improves …