Perinatal necrotizing enterocolitis
MONDO:0004639A fulminating disease of neonates in which there is extensive mucosal ulceration, pseudomembrane formation, submucosal hemorrhage, and necrosis usually of the right colon, cecum, terminal ileum, and appendix, possibly due to perinatal intestinal ischemia and bacterial invasion. Progression can lead to necrosis, perforation and/or scarring of the intestinal tract.
Also known as: enterocolitis necrotizing, necrotizing enterocolitis, necrotizing enterocolitis in foetus or newborn, enterocolitis, necrotizing
13 clinical trials for this condition and its sub-types.
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NIH launches massive GI data bank to fuel future discoveries
Knowledge-focused Recruiting nowThis study aims to collect medical data and biological samples (blood, urine, stool, and tissue) from up to 4,000 adults with known or suspected gastrointestinal diseases. Participants receive standard medical care at the NIH, and any extra samples or leftover tissue from procedu…
Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Cord blood clues could spot preemie health threats early
Knowledge-focused Recruiting nowThis study looks at tiny particles called extracellular vesicles in the umbilical cord blood of extremely premature babies (born before 28 weeks). Researchers want to see if these particles can help predict serious problems like brain bleeding, lung injury, or death. The goal is …
Sponsor: University Hospital, Montpellier • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC
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Scientists dive into amniotic fluid to unlock preterm gut mysteries
Knowledge-focused Recruiting nowThis study collects amniotic fluid from 275 pregnant women delivering at various stages, including extremely preterm. Researchers will analyze the fluid's microbes and chemicals, and link them to the baby's gut bacteria and health outcomes like necrotizing enterocolitis (NEC) and…
Sponsor: Maxima Medical Center • Aim: Knowledge-focused
Last updated Jun 26, 2026 13:16 UTC