Tiny patients, big questions: antibiotic levels in infant bowel surgery
NCT ID NCT04299867
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at how the antibiotic metronidazole spreads into the intestinal tissue of 21 infants (ages 0-2) during planned bowel surgery. Researchers took blood and tissue samples at several time points to measure drug levels. The goal is to find the best dose to prevent infections after surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Metronidazole
What this could lead to
If successful, this could help doctors give the right dose of metronidazole to infants during bowel surgery to prevent infections.
What could go wrong
This is a small, early study with only 21 infants, so results may not apply to all babies. It measures drug levels, not whether infections are actually prevented.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Duke University Health System
Durham, North Carolina, 27710, United States