Sugar and stress: could fructose malabsorption fuel anxiety?

NCT ID NCT05371067

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at whether difficulty digesting fructose (a sugar found in many foods) is linked to anxiety and changes in gut bacteria. Researchers compared 56 healthy young men who either absorb fructose normally or have trouble absorbing it. The goal was to see if fructose malabsorption affects mood and the gut microbiome, without any treatment being tested.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

fructose respiratory test

What this could lead to

If successful, this could point toward dietary strategies for managing anxiety linked to gut health.

What could go wrong

This is a small, completed observational study in healthy young men only, so results may not apply to broader populations or confirm cause and effect.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Digestive System Diseases digestive system disorder intestinal disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHU de ROUEN

    Rouen, Rouen, 76000, France