Sugar and stress: could fructose malabsorption fuel anxiety?
NCT ID NCT05371067
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at whether difficulty digesting fructose (a sugar found in many foods) is linked to anxiety and changes in gut bacteria. Researchers compared 56 healthy young men who either absorb fructose normally or have trouble absorbing it. The goal was to see if fructose malabsorption affects mood and the gut microbiome, without any treatment being tested.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- fructose respiratory test
- What this could lead to
- If successful, this could point toward dietary strategies for managing anxiety linked to gut health.
- What could go wrong
- This is a small, completed observational study in healthy young men only, so results may not apply to broader populations or confirm cause and effect.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
CHU de ROUEN
Rouen, Rouen, 76000, France
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