Which drug gets your gut moving faster after bowel surgery?

NCT ID NCT06112353

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two medications used to reverse muscle relaxants after bowel surgery: Sugammadex versus Neostigmine with Glycopyrrolate. The goal is to see which one helps patients have their first bowel movement and tolerate solid food sooner. About 128 adults undergoing laparoscopic bowel resection will be randomly assigned to one of the two drugs, and researchers will track recovery time, hospital stay length, and costs.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Sugammadex injection and Neostigmine Injectable Solution (with Glycopyrrolate)
What this could lead to
If it works, this could help patients recover bowel function faster after surgery, potentially shortening hospital stays and reducing costs.
What could go wrong
This is a small, early-phase trial (128 participants) comparing two existing drugs, so any benefit may be modest or not apply to all patients. Risks include side effects like slowed heart rate.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • UC Irvine Medical Center

    RECRUITING

    Orange, California, 92868, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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