Bruxism
MONDO:0002443Excessive clenching of the jaw and grinding of the teeth.
Also known as: bruxism, bruxism (disease), sleep related bruxism
68 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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Face shape may predict botox success for teeth grinders
Disease control CompletedThis study looks at whether the shape of a person's face influences how Botox injections change bite force in people who grind their teeth (bruxism). Participants with different facial structures receive Botox into the jaw muscle, and bite force is measured before and after treat…
Phase: NA • Sponsor: Biruni University • Aim: Disease control
Last updated Jul 01, 2026 00:00 UTC
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New device zaps teeth grinding with vibrations
Disease control CompletedThis completed trial tested a device called AesyBite Active, which uses gentle vibrations to reduce teeth grinding (sleep bruxism) during the night. 26 adults who grind their teeth wore the device while sleeping. The main goal was to see if it could cut grinding activity by at le…
Phase: NA • Sponsor: Aesyra SA • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
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New splint aims to diagnose teeth grinding accurately
Diagnosis CompletedThis study tested a new device called the BRUXENSE occlusal splint to see if it can help diagnose sleep bruxism (teeth grinding). Seven adults with bruxism tried wearing the splint for 10 nights. The goal was to see if they could use it comfortably and if it collected enough data…
Phase: NA • Sponsor: Hospices Civils de Lyon • Aim: Diagnosis
Last updated Jun 27, 2026 08:05 UTC
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Can video coaching boost jaw exercise results for teeth grinders?
Symptom relief CompletedThis trial investigates whether jaw exercises (Rocabado programme) work better when guided by a physiotherapist through online video sessions versus doing them at home with written instructions alone. Adults aged 18-60 with jaw-joint pain and teeth grinding are randomly assigned …
Phase: NA • Sponsor: Mehmet Turgut • Aim: Symptom relief
Last updated Jul 02, 2026 00:00 UTC
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Needles vs. botox: which eases grinding pain best?
Symptom relief CompletedThis study tested three treatments for chronic teeth grinding (bruxism): dry needling and two types of botulinum toxin (Botox). 72 adults with severe jaw pain were split into three groups. Researchers measured pain levels and jaw muscle thickness before treatment and up to 3 mont…
Phase: NA • Sponsor: Recep Tayyip Erdogan University • Aim: Symptom relief
Last updated Jun 27, 2026 12:35 UTC
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Botox vs. mouthguards: which eases grinding pain best?
Symptom relief CompletedThis study tested three ways to treat jaw pain caused by teeth grinding (bruxism): a custom mouthguard (occlusal splint), Botox injections, or both together. Sixty adults completed the 3-month trial. Researchers measured pain and jaw function changes to see which approach worked …
Phase: PHASE4 • Sponsor: Recep Tayyip Erdogan University • Aim: Symptom relief
Last updated Jun 27, 2026 12:33 UTC
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Deep cleaning may soothe jaw pain for teeth grinders with gum disease
Symptom relief CompletedThis study looked at whether a deep dental cleaning (called subgingival instrumentation) can reduce jaw symptoms like pain, stiffness, and tension in people who grind their teeth (bruxers) and also have gum disease (periodontitis). Sixty adults aged 30-40 received the cleaning, a…
Phase: NA • Sponsor: Postgraduate Institute of Dental Sciences Rohtak • Aim: Symptom relief
Last updated Jun 27, 2026 12:31 UTC
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New sleep supplement tested in 60 adults – results pending
Symptom relief CompletedThis study tested a dietary supplement called Speed Sleep in 60 adults aged 18-65 who have trouble sleeping. Participants took either the supplement or a placebo daily for 4 weeks. Sleep quality and quantity were measured using Fitbit trackers and questionnaires.
Phase: NA • Sponsor: Bio Nature Health • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
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Botox for jaw pain: ultrasound reveals muscle changes in teeth grinders
Symptom relief CompletedThis small study looked at 17 adults with bruxism (teeth grinding) who received Botox injections into their jaw muscle. Researchers used ultrasound to measure muscle thickness and texture before treatment, at 14 days, and at 90 days. They also tracked pain levels. The goal was to…
Phase: NA • Sponsor: Kahramanmaras Sutcu Imam University • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Needles vs. night guards: which eases Jaw-Grinding pain best?
Symptom relief CompletedThis study looked at two treatments for jaw pain caused by teeth grinding (bruxism) and related muscle pain. Forty adults either got a custom mouth splint to wear most of the day or had thin needles inserted into their jaw muscles (dry needling) in three weekly sessions. Research…
Phase: NA • Sponsor: Kocaeli University • Aim: Symptom relief
Last updated Jun 27, 2026 12:06 UTC
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Herbal sleep aid shows promise in midlife insomnia trial
Symptom relief CompletedThis study tested whether a daily mix of plant protein and two herbs (ashwagandha and rhodiola) could improve sleep in 100 adults aged 35-70 with sleep troubles. Participants took either the supplement or a placebo for 30 days and reported their sleep quality daily. The goal was …
Phase: NA • Sponsor: Universidad Pablo de Olavide • Aim: Symptom relief
Last updated Jun 27, 2026 11:00 UTC
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Sleep aid boosts immunity in small trial
Symptom relief CompletedThis early study tested a product called Chenghuang Circadian Rhythm Regulator in 15 adults with ongoing sleep problems. The goal was to see if it could improve sleep quality and immune markers. Results are not yet reported, but the study was small and had no comparison group.
Phase: NA • Sponsor: Shanghai Cell Therapy Group Co.,Ltd • Aim: Symptom relief
Last updated Jun 27, 2026 09:05 UTC
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Headband that reads your brain waves may ease insomnia in menopausal women
Symptom relief CompletedThis study tested whether a headband called Muse-S, which senses brain activity, could help midlife women with sleep problems like insomnia. Thirty-one women going through menopause wore the device at home. The goal was to see if it was practical and if it improved sleep quality …
Phase: NA • Sponsor: Mayo Clinic • Aim: Symptom relief
Last updated Jun 27, 2026 08:14 UTC
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High-Tech mouthguards aim to stop teeth grinding pain
Symptom relief CompletedThis study tested whether custom mouthguards (splints) designed using a 3D jaw-tracking device called MODJAW work better than standard mouthguards for people with teeth grinding (bruxism) or jaw pain. 40 adults with mild-to-moderate symptoms wore either a personalized or standard…
Phase: NA • Sponsor: Istanbul University • Aim: Symptom relief
Last updated Jun 27, 2026 08:13 UTC
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Botox vs. splints: which stops teeth grinding best for denture wearers?
Symptom relief CompletedThis study tested three ways to manage sleep bruxism (teeth grinding) in 48 people with implant-supported dentures. One group got Botox injections into the jaw muscles, another used a custom mouth splint at night, and a third simply removed their dentures at night (control). Rese…
Phase: PHASE1 • Sponsor: Delta University for Science and Technology • Aim: Symptom relief
Last updated Jun 27, 2026 08:13 UTC
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Simple jaw exercises may offer Drug-Free relief for jaw pain sufferers
Symptom relief CompletedThis study tested whether a combination of a specific jaw muscle technique and neck exercises could reduce pain and improve jaw function in people with temporomandibular disorder (TMD) and teeth grinding (bruxism). Sixty adults with TMD and bruxism were split into two groups: one…
Phase: NA • Sponsor: Instituto de Investigación Biomédica de Salamanca • Aim: Symptom relief
Last updated Jun 27, 2026 08:06 UTC
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Gentle pressure, deep sleep: acupressure shows promise for elderly insomnia
Symptom relief CompletedThis study tested whether acupressure—a gentle finger-pressure technique on specific body points—could improve sleep in elderly people living in care homes. 75 residents took part, with half receiving 12 acupressure sessions over four weeks. The results showed that those who rece…
Phase: NA • Sponsor: Duzce University • Aim: Symptom relief
Last updated Jun 27, 2026 08:05 UTC
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New online course helps seniors kick the benzo habit
Symptom relief CompletedThis study tested an online program called ALDER that teaches older adults skills to boost positive emotions and reduce anxiety. 33 people aged 65 and older who used benzodiazepines (anti-anxiety or sleep medications) at least twice a week took part. Over 5 weeks, they learned an…
Phase: NA • Sponsor: Northwestern University • Aim: Symptom relief
Last updated Jun 27, 2026 08:04 UTC
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Breathe easy, grind less: simple breathing exercises may ease nighttime teeth clenching
Symptom relief CompletedThis study tested whether a 4-week program of diaphragmatic breathing exercises before bed can reduce sleep bruxism (teeth grinding) in 100 adults. Participants learned deep breathing techniques and practiced them nightly, while a control group listened to neutral music. The goal…
Phase: NA • Sponsor: University of Monastir • Aim: Symptom relief
Last updated Jun 27, 2026 07:57 UTC
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Better sleep could ease severe mental illness symptoms, study finds
Symptom relief CompletedThis study tested a sleep and circadian treatment (TranS-C) for people with severe mental illness (SMI) in community mental health centers. The treatment was adapted to better fit these settings. Researchers looked at whether it improved sleep, daily functioning, and symptoms in …
Phase: NA • Sponsor: University of California, Berkeley • Aim: Symptom relief
Last updated Jun 27, 2026 07:55 UTC
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Better sleep, better mental health: new training approach tested in community clinics
Symptom relief CompletedThis study tested two versions of a sleep treatment for people with severe mental illness in community mental health centers. One version was the standard treatment, and the other was adapted to better fit patients' needs. The goal was to see if training clinic staff to deliver t…
Phase: NA • Sponsor: University of California, Berkeley • Aim: Symptom relief
Last updated Jun 27, 2026 07:55 UTC
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Botox or aromatherapy? new study pits two treatments against sleep grinding
Symptom relief CompletedThis study compared two treatments for sleep bruxism (teeth grinding): botox injections and marjoram oil aromatherapy. Thirty adults with sleep bruxism were split into two groups, receiving either botox or marjoram oil. Researchers measured changes in jaw muscle thickness, pain, …
Phase: NA • Sponsor: Bezmialem Vakif University • Aim: Symptom relief
Last updated Jun 26, 2026 18:48 UTC
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Jaw pain from teeth grinding? hands-on therapy and simple exercises may help
Symptom relief CompletedThis study tested two non-drug approaches for bruxism (teeth grinding) in 30 young adults. One group received hands-on manual therapy to the jaw and neck, while the other did home exercises. Both groups also learned about bruxism. The goal was to see if these treatments could red…
Phase: NA • Sponsor: Bartın Unıversity • Aim: Symptom relief
Last updated Jun 26, 2026 16:41 UTC
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Whistle blowing: Referees' jaw troubles under the microscope
Knowledge-focused CompletedThis study looked at jaw disorders and teeth grinding in 76 elite basketball referees compared to healthy people. Referees face high stress and often hold a whistle between their teeth, which may strain the jaw. Researchers used ultrasound to measure jaw muscle thickness and foun…
Sponsor: Istanbul Physical Medicine Rehabilitation Training and Research Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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Nerve activity linked to jaw muscle stiffness in bruxism study
Knowledge-focused CompletedThis study looked at 89 people — some with bruxism (teeth grinding) and some healthy — to see if there is a connection between the body's 'automatic' nervous system and the tightness, stiffness, and elasticity of the chewing muscles. Participants wore a chest strap to measure hea…
Sponsor: Bandırma Onyedi Eylül University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:32 UTC
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Teeth grinding linked to poor posture and jaw pain in new study
Knowledge-focused CompletedThis study looked at 48 young adults (24 with bruxism, or teeth grinding, and 24 without) to understand how jaw function, posture, muscle stiffness, pain, stress, and sleep quality are connected. Researchers used special tools to measure posture, muscle tightness, and pain levels…
Sponsor: Istanbul Kent University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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Smart system aims to crack brain disorder diagnosis
Knowledge-focused CompletedThis study tested a computer system designed to help doctors more accurately diagnose and manage complex brain disorders like dementia, epilepsy, and sleep problems. Researchers collected health data from 635 people visiting specialty clinics, including healthy volunteers, to see…
Sponsor: Neurological Institute of Athens • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
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Can your smartwatch detect teeth grinding at night?
Knowledge-focused CompletedThis study used smartwatches to compare sleep stages and total sleep time between 62 adults with sleep bruxism (teeth grinding) and healthy controls. Participants wore a smartwatch for 7 nights to collect sleep data. The goal was to see if smartwatches can help monitor sleep brux…
Sponsor: Cappadocia University • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Grinding your teeth? it might be hurting your lungs and balance too
Knowledge-focused CompletedThis study looked at whether people with bruxism (teeth grinding or clenching) have worse lung function, breathing muscle strength, balance, and sleep quality compared to healthy people. Researchers tested 34 adults using breathing tests, balance assessments, and sleep questionna…
Sponsor: Gazi University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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Botox for grinding teeth: does it change jaw muscle over time?
Knowledge-focused CompletedThis study looked at 27 adults with sleep bruxism (teeth grinding) who got Botox injections in their jaw muscles every six months for two years. Researchers used ultrasound to measure fat buildup in the muscle before each injection. The goal was to see if repeated Botox causes lo…
Phase: NA • Sponsor: Melek Volkan Yazici • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:02 UTC
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Gum therapy may ease teeth grinding, small study hints
Knowledge-focused CompletedThis study tested whether treating severe gum disease (periodontitis) with a deep cleaning procedure could also reduce teeth grinding (bruxism) during the day and night. Forty adults with advanced gum disease or healthy gums took part. Researchers measured grinding events before …
Phase: NA • Sponsor: University of Siena • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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Gum disease and nighttime teeth grinding: is there a connection?
Knowledge-focused CompletedThis completed study looked at whether people with advanced gum disease (periodontitis) also grind or clench their teeth more during sleep. Researchers used a small portable device to measure muscle activity in the jaw over 24 hours in 40 adults, half with severe gum disease and …
Sponsor: University of Siena • Aim: Knowledge-focused
Last updated Jun 26, 2026 13:30 UTC