Bruxism

This study tests whether a digital bite-force sensor can objectively measure bruxism (teeth grinding) and track how well Botox injections work. Thirty-six adults with bruxism will receive either Botox or a placebo in their jaw muscles. Researchers will use the sensor and patient …

This study tests whether a drug called gamma-hydroxybutyrate (GHB) can help intensive care patients get better deep sleep. Sleep problems are very common in the ICU and can lead to serious issues like confusion and longer recovery. The trial will give GHB or a placebo to 24 adult…

This study tests a special gel (HA35) applied to the jaw at night to relieve pain and muscle tightness from temporomandibular joint disorder (TMD). About 30 adults with TMD will use the gel nightly for 8-12 hours. Researchers will check how well it reduces pain and tension after …

This study tests a slow-release melatonin (PedPRM) in 120 children aged 6 to 18 who have anorexia nervosa and trouble sleeping. Participants take either melatonin or a placebo for 13 weeks. The goal is to see if it safely improves total sleep time and related symptoms like anxiet…

This study will test whether different massage techniques can reduce jaw pain and muscle stiffness in people with sleep bruxism (teeth grinding). Forty-two participants will receive either connective tissue massage, another massage method, or a standard mouthguard (occlusal splin…

This study looks at whether adding sleep-focused treatments to standard psychiatric care can reduce suicide risk in young adults. About 90 college students with suicidal thoughts and sleep problems will be randomly assigned to one of three sleep interventions. Researchers will tr…

This study looks at whether adding stress management and sleep education to standard physiotherapy can help people with temporomandibular disorders (TMD). TMD causes jaw pain, teeth grinding, and sleep problems. Forty adults with TMD will receive either physiotherapy alone or phy…

This study looks at how mental health, especially stress, affects gum disease in people who grind their teeth. About 110 adults aged 30-50 with both teeth grinding and gum disease will answer mental health questions and get a dental check-up. The goal is to see if poor mental hea…

This study looks at how stress levels, sleep quality, and teeth grinding (bruxism) together affect gum disease in adults aged 30-45. Researchers will compare two groups of people with gum disease: those who grind their teeth and those who do not. The goal is to understand how the…

This study looks at whether psychological resilience — the ability to bounce back from stress — can reduce the harmful effects of stress on gums in people who grind their teeth (bruxers). Researchers will measure stress and resilience using questionnaires and check gum health in …

This study looks at how the size of the upper airway might influence teeth grinding (bruxism) during sleep in people with obstructive sleep apnea. Researchers will use safe, low-radiation 3D scans and sleep tests to measure airway volume and bruxism in 80 adults. The goal is to b…

This study explores whether stress in children and their parents is related to bruxism (teeth grinding) in kids aged 8-11. Researchers will compare 100 children with and without bruxism, using questionnaires to measure stress levels. The goal is to better understand the role of s…

This study will track 100 adults receiving a single dental implant to see if the implant moves between placement and the final crown, about 3-4 months later. Researchers will use 3D scans taken right after surgery and before loading the crown to measure any shifts in position or …