Botox for grinding teeth: does it change jaw muscle over time?

NCT ID NCT07266064

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 27 adults with sleep bruxism (teeth grinding) who got Botox injections in their jaw muscles every six months for two years. Researchers used ultrasound to measure fat buildup in the muscle before each injection. The goal was to see if repeated Botox causes long-term structural changes in the jaw muscle.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
botulinum toxin type A (Botox)
What this could lead to
If it works, this could help doctors understand the long-term safety of repeated Botox injections for teeth grinding.
What could go wrong
This is a small, completed study with only 27 people, so results may not apply to everyone. It looks at muscle changes, not whether the treatment works for symptoms.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for BRUXISM are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Ankara University, Faculty of Dentistry

    Ankara, Cankaya, 06560, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.