Botox for grinding teeth: does it change jaw muscle over time?
NCT ID NCT07266064
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at 27 adults with sleep bruxism (teeth grinding) who got Botox injections in their jaw muscles every six months for two years. Researchers used ultrasound to measure fat buildup in the muscle before each injection. The goal was to see if repeated Botox causes long-term structural changes in the jaw muscle.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
botulinum toxin type A (Botox)
What this could lead to
If it works, this could help doctors understand the long-term safety of repeated Botox injections for teeth grinding.
What could go wrong
This is a small, completed study with only 27 people, so results may not apply to everyone. It looks at muscle changes, not whether the treatment works for symptoms.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Ankara University, Faculty of Dentistry
Ankara, Cankaya, 06560, Turkey (Türkiye)