Botox or aromatherapy? new study pits two treatments against sleep grinding

NCT ID NCT06674733

Completed Symptom relief Sponsor: Bezmialem Vakif University Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study compared two treatments for sleep bruxism (teeth grinding): botox injections and marjoram oil aromatherapy. Thirty adults with sleep bruxism were split into two groups, receiving either botox or marjoram oil. Researchers measured changes in jaw muscle thickness, pain, and sleep quality over three months to see which approach worked better.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: botulinum toxin-A (Botox) and marjoram oil
What this could lead to: If successful, this could point toward a non-surgical treatment option for sleep bruxism, potentially easing jaw pain and improving sleep quality.
What could go wrong: This is a small, early study with only 30 participants, so results may not apply to everyone. Botox injections carry risks like muscle weakness, and marjoram oil's effectiveness is not well proven.

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Conditions

The condition(s) this trial relates to.

bruxism parasomnia, sleep bruxism type Sleep Bruxism

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BRUXISM, SLEEP

Contacts and locations

Locations

Bezmialem Vakif University

Istanbul, Fatih, 34093, Turkey (Türkiye)

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