University Of Utah

This study tested whether lifestyle coaching delivered through a patient portal helps adults maintain weight loss. 269 participants who had already lost at least 5% of their body weight were randomly assigned to receive either coaching plus tracking tools or tracking tools alone …

This phase II trial tested a 9-day course of whole breast radiation (hypofractionated radiotherapy) in 102 patients with early-stage breast cancer (stages 0-IIB). The goal was to see if a shorter treatment schedule could maintain good cosmetic outcomes and quality of life while r…

This study tested a cream containing acyclovir and penciclovir against an over-the-counter cream (Abreva) for preventing cold sores caused by UV light. Forty adults with a history of cold sores were exposed to UV light to trigger an outbreak, then treated with one of the creams. …

This study tested whether EDTA eye drops can shorten cold sore outbreaks compared to the over-the-counter cream Abreva. Ten adults with a history of sun-triggered cold sores were randomly assigned to one of the two treatments. Researchers tracked how many days it took for each co…

This study tested whether using a wound protector during shoulder replacement surgery lowers the chance of bacterial contamination. One hundred patients were randomly assigned to receive surgery with or without the device. The goal was to see if the protector reduces deep wound b…

This study looked at whether it's practical to give a blood thinner (low molecular weight heparin) to women after a C-section to prevent blood clots. Researchers enrolled 64 women and compared those who got the drug to those who got no treatment. The main goal was to see if enoug…

This study tested whether doing balance exercises 3 times a week for 4 weeks works as well as doing them 2 times a week for 6 weeks in people with chronic ankle instability. 57 adults with weak, unstable ankles were randomly assigned to one of the two training groups or a waitlis…

This study looked at whether a fast blood test (ROTEM) done during surgery for placenta accreta can help doctors decide when to give blood transfusions. 32 women took part, with half getting the rapid test and half getting standard lab tests. The goal was to see if the rapid test…

This early study tested whether placing a thin layer of human amniotic membrane (the tissue that surrounds a baby in the womb) on the heart during bypass surgery could reduce inflammation and lower the chance of developing atrial fibrillation (a common irregular heartbeat) after …

This early-phase trial tested a combination of two drugs (MEK162 and mFOLFIRI) in 25 adults with advanced RAS-positive colorectal cancer that had stopped responding to standard treatment. The main goal was to find the safest dose and check for side effects. Researchers also looke…

This study tested a program to help adults who take prescribed opioid medications also reduce their alcohol use. 112 people who filled opioid prescriptions at community pharmacies and reported current alcohol use took part. The program adapted an existing intervention for opioid …

This study tested whether a diode laser can act as a biomarker to measure neuropathic pain in people with peripheral neuropathy. Researchers compared pain responses to a lidocaine patch versus a placebo patch in 75 participants. The goal was to see if the laser test could disting…

This study tested a tool called MyLungHealth, which is delivered through a patient's online health portal. The goal was to see if it could help more people who are at high risk for lung cancer get the recommended low-dose CT scan. Over 31,000 people aged 50-79 with a history of s…

This study tested whether a mindfulness-based training program could help adults who had lost weight keep it off. 48 participants, including those who had bariatric surgery or lost weight through medical or lifestyle programs, took part. The goal was to see if focusing on eating …

This early-phase study tested whether a hormone called progesterone could help new mothers avoid returning to methamphetamine use after childbirth. 34 postpartum women with a history of meth use but currently abstinent took either progesterone or a placebo for 12 weeks. The goal …

This study tested a program called SHINE to help high school students use more sun protection and tan less. Over 2,200 students from 30 schools in Utah took part. Half the schools got the SHINE program, and the other half got standard lessons. The goal was to see if the program c…

This study tested a smartphone app that gives parents and children real-time feedback on the child's exposure to ultraviolet (UV) radiation from the sun. The goal was to encourage better sun protection habits, like using sunscreen or wearing protective clothing, to lower the risk…

This study tested two practical methods to increase COVID-19 vaccination among over 65,000 patients at Utah community health centers. One group received text message reminders to get vaccinated, while another group got texts plus a personal navigator to help with logistics like s…

This study tested a simple text-message program to help parents in rural areas get their children ages 9-17 vaccinated against HPV, a virus that can cause cancer. Researchers worked with four community clinics in Washington to see if this approach was practical and could increase…

This study tested a sun safety program for high school students in rural Utah. The program included in-class lessons and was designed to be easy for schools to continue on their own. Researchers surveyed 38 students before and one month after the program to see if they used more …

This study tested a program called EnACT for family caregivers of people with dementia. The program uses group sessions where caregivers watch scenarios, practice responses, and reflect on their choices. The goal is to help caregivers feel more prepared and less stressed when dea…

This study tested whether Reiki (a hands-on energy therapy), sham Reiki (a placebo version), or mindfulness meditation can help reduce pain and stiffness in people with knee osteoarthritis. 164 adults with knee osteoarthritis were randomly assigned to one of four groups: Reiki, s…

This study looked at whether taking a whey protein supplement twice a day helps adolescent soccer players improve their performance, recover faster, and change body composition during a 10-12 week competitive season. Thirty-one high school players aged 13-18 took either the prote…

This study tested whether injecting amniotic fluid into the spine can safely reduce pain and disability in people with spinal stenosis who haven't found relief from other treatments. 61 adults received either an amniotic fluid injection or a standard steroid injection. The goal w…

This study tested whether a low-cost version of platelet-rich plasma (PRP) injections could safely ease joint pain and swelling in people with bleeding disorders like hemophilia. Fourteen adults with joint damage received the injection and were followed for 6 months. The goal was…

This study tested a device that sends sound from the non-hearing ear to a cochlear implant in the other ear. 16 older adults with one cochlear implant used the device to see if it improved their speech understanding in noisy settings. The goal was to also see if it improved quali…

This study tested a drug called dexmedetomidine in 50 newborns with brain injury who were undergoing cooling therapy. The goal was to see if it could provide sedation and pain relief as well as morphine, but with fewer risks. Researchers measured safety and drug levels in the blo…

This study tested different treatment sequences for chronic low back pain in 749 adults. Participants first received either physical therapy or cognitive behavioral therapy. Those who didn't improve were switched to the other therapy or added mindfulness. The goal was to find whi…

This study compared two injections for sacroiliac joint pain: platelet-rich plasma (PRP) made from the patient's own blood, and a standard steroid/anesthetic mix. Fifty adults with confirmed sacroiliac joint pain received one of the two injections. Researchers measured pain level…

This pilot study tested whether radiofrequency ablation (RFA) of the genicular nerves can reduce chronic knee pain in people who had a total knee replacement at least a year ago. Five participants with moderate to severe pain received the procedure. The goal was to see if RFA pro…

This study tested whether special medicated cloths (Qbrexza) can reduce excessive sweating at the amputation site in 13 limb amputees. Participants used either the active cloth or a placebo for 4 weeks, then switched after a 2-week break. The goal was to see if less sweating impr…

This study tested whether a personalized exercise program helps people with early-stage lung cancer or cancer that spread to the lungs recover better after surgery. 182 participants were randomly assigned to either the exercise program or usual care. The main goal was to see if t…

This study tested a new, low-cost way to make platelet-rich plasma (PRP) from a patient's own blood for treating knee osteoarthritis. Twenty adults with mild to moderate knee arthritis received two injections of this low-cost PRP. Researchers checked if the PRP had enough platele…

This study compared a single injection of sterile amniotic fluid to the standard steroid shot for knee osteoarthritis. 60 adults with moderate knee arthritis who had not gotten relief from other treatments took part. The main goal was to see if the amniotic fluid could reduce the…

This study tested whether exercise, with or without internet-based cognitive behavior therapy, could reduce fatigue in 126 men with advanced prostate cancer. Participants were on hormone therapy and followed a 12-week exercise program. The goal was to see if these non-drug approa…

This study tested whether a shot of platelet-rich plasma (PRP) made from a person's own blood can reduce hip pain and improve movement in people with a torn hip labrum. Thirty adults aged 18 to 49 who had not gotten better with other treatments took part. Researchers tracked pain…

This early-phase study tested whether taking atorvastatin (a cholesterol medicine) for a week before misoprostol can safely end an early pregnancy. Nine women between 5-7 weeks pregnant participated. The goal was to see if the combination interferes with pregnancy progress. This …

This study tested a new type of talk therapy called Emotional Awareness and Expression Therapy (EAET) for people with migraines. 30 adults with frequent migraines took part in 8 weekly online sessions to see if it could lower how often and how bad their headaches were. The goal w…

This study looked at how a natural hemp extract cosmetic product, containing CBD in coconut oil, enters the blood when applied to the skin or taken by mouth. Twenty healthy adults each tried both methods, with a 15-day break in between. Researchers measured CBD, THC, and their br…

This small, completed study looked at how many Hydrus microstent surgeries glaucoma fellows need to perform before they become skilled. Researchers graded videos of surgeries from 5 fellows at three eye centers. The goal was to find the average number of cases needed to reach an …

This study looked at 120 adults who had total knee replacement surgery to compare four different types of knee implants. Researchers measured how well patients could walk, climb stairs, and stand up from a chair, along with their own reports of pain and function. The goal was to …

This study tested a wireless insole device (Loadsol) in 58 people who had hip or knee replacement surgery. The goal was to see if the device could accurately measure how much weight they put on their leg while walking and if giving feedback could help improve their walking symmet…

This study looked at how periods of reduced activity, like after surgery or injury, affect blood vessel and muscle function in older adults. Researchers measured blood flow in the arm and leg using ultrasound. The goal was to understand the role of oxidative stress in these chang…

This study tested a virtual educational program designed to help members of organizations that work with autistic people learn how to support suicide prevention. 51 participants completed surveys before, after, and 3 months after the training, and some gave optional interviews. T…

This completed study from the University of Utah tested how accurately a practitioner can locate a rib by touch (palpation) for dry needling of deep shoulder muscles. Using ultrasound as a gold standard, researchers compared the practitioner's guess to the actual rib location in …

This study tested whether an educational website helps people who stopped taking statins due to muscle pain make informed decisions about restarting. Nearly 900 participants were randomly assigned to use the website or receive usual care. The goal was to see if the website increa…

This study looked at whether cochlear implants, devices that help people hear, can also improve thinking and memory in adults aged 65 and older with hearing loss. Researchers gave participants memory and attention tests before getting the implant, then again at 6 months, 1 year, …

This study looked at whether different social media messages can motivate people to follow colon cancer screening guidelines. Over 2,000 adults who identified as White or Black/African American completed a survey after seeing one of five message types. The goal was to see which m…

This study explored whether adding mindfulness training to physical therapy is practical for people with long-term muscle and joint pain who also take opioid painkillers. Researchers developed a training manual for physical therapists and tested different ways to teach them mindf…

This study looked at how lifestyle factors like obesity and muscle loss affect kidney cancer risk and survival after kidney removal. Researchers collected blood, tissue, and questionnaire data from 161 patients over up to 5 years. The goal was to understand how to personalize tre…

This study looked at how hormonal birth control might help manage inflammatory bowel disease (IBD) symptoms that get worse during a woman's period. Researchers surveyed 50 women with IBD to understand their preferences for birth control and whether they would join a future trial.…

This study tested whether a new software program helps doctors more accurately interpret ROTEM blood clotting tests. Twenty-six doctors and residents from the University of Utah took part. Researchers compared their answers before and after using the software to see if it improve…

This study looked at how to best communicate risks and benefits to parents of children with multiple health conditions. Over 800 caregivers watched videos of a doctor visit and answered surveys. The goal was to see which information helped parents feel more ready to make a decisi…

This study looked at whether a daily probiotic supplement could help teenagers who feel moderate stress. Researchers measured changes in mood, thinking skills (like memory and attention), and immune markers in 104 teens aged 12-20. The goal was to understand how probiotics might …

This study tested whether sending text messages can help more people get screened for lung cancer. 65 adults aged 50-80 who were current or former smokers took part. The program used a central system to check who was eligible, offer risk assessments, and help schedule screening. …

This study looked at which online messages about colon cancer screening are most convincing and likely to be shared. Over 2,200 Black and White Americans aged 45-74 rated different messages from websites. The goal was to find the best ways to encourage people to follow screening …

This study looked at whether combining brain, nerve, and hand stimulation can improve the connection between the brain and weak hand muscles in people who had a stroke at least six months ago. 51 adults with chronic stroke participated. The goal was to measure changes in brain-to…

This study tested a training program for labor and delivery providers in Tanzania to reduce HIV stigma during childbirth. The training used simulations and hands-on learning to help providers offer more respectful care. Researchers compared how women rated their care before and a…

This study looked at over 3,000 people with a family history of certain cancers to see if a patient-directed model (where patients order their own genetic test) leads to more testing than the standard model (which requires a genetic counselor visit first). The goal was to see whi…

This study looked at 38 adults who usually sleep less than 6 hours a night. Researchers helped them increase their sleep to the recommended 7 hours and measured changes in blood chemicals and insulin sensitivity. The goal was to find biological markers that can tell if someone is…

This study looked at 270 women who had unprotected sex and then started a highly effective birth control method (like an IUD or implant) 6 to 14 days later. The goal was to find out how many got pregnant in the first month. The results help doctors and patients understand the ris…

This study compared two methods to increase COVID-19 testing among patients at Utah community health centers: text message reminders alone versus text messages plus a patient navigator who helped with logistics. Over 44,000 English- or Spanish-speaking adults with a working cell …