University Of Utah

This early-phase study tests whether adding ropeginterferon alfa-2b to the standard drug ruxolitinib is safe for people with myelofibrosis, a type of bone marrow cancer. About 15 adults already on a stable dose of ruxolitinib will receive the added drug. The main goal is to check…

This study tests whether combining two drugs, mosunetuzumab and pirtobrutinib, is safe and works for people with Waldenstrom macroglobulinemia whose cancer returned or didn't respond to prior therapy. About 25 adults will receive the combination to find the best dose and measure …

This study looks at whether estrogen patches can help post-menopausal women recover better after rotator cuff surgery. About 58 women will receive either estrogen or placebo patches after their operation. The goal is to see if the patches improve shoulder pain, strength, and func…

This study tests whether adding the anti-inflammatory drug piroxicam to the standard emergency contraceptive pill levonorgestrel prevents pregnancy better than levonorgestrel alone. About 1,458 women aged 16-35 who had unprotected sex within 72 hours will take either the combinat…

This early-stage trial tests whether giving radiation therapy before a bispecific antibody drug (epcoritamab or glofitamab) is safe for people with a type of aggressive lymphoma (DLBCL) that has come back or not responded to at least two prior treatments. The study will enroll 12…

This study is testing a new blood test that looks at genetic material in platelets to find lung cancer. Researchers want to see if the test can accurately detect cancer and tell the difference between harmless and cancerous lung nodules. The study will enroll 240 adults who eithe…

This study tests a non-drug therapy called imagery rehearsal therapy to see if it can reduce nightmares in adults with narcolepsy. About 80 people with narcolepsy will take part, along with their romantic partners. Everyone gets the therapy, but at different times, and they fill …

This study looks at whether having a paracentesis (draining fluid from the belly) at home can improve symptoms for women with cancer-related ascites. About 20 women who have already had the procedure in a clinic will try it at home. Researchers will measure changes in symptom sco…

This study will test a new positive airway pressure (PAP) system in 25 healthy volunteers. The goal is to see how accurately the system measures breathing and maintains airway pressure, and how comfortable it is. This is not a treatment study—it aims to gather data to improve the…

This study looks at three ways to give oxygen during colonoscopy sedation to find which one best prevents breathing pauses and drops in oxygen levels. About 280 adults will be randomly assigned to standard continuous flow oxygen, a new synchronized pulse device, or a CPAP mask. T…

This study tests a new chatbot that gives cancer patients and their caregivers clear information about insurance, travel costs, and other financial issues. About 60 adults from rural areas in five states will use either a hybrid or AI-only chatbot. The goal is to see if the chatb…

This study tests whether a new educational tool helps patients on blood thinners (anticoagulants) learn more about their medication. About 68 participants will either use the new tool or the standard materials and then answer surveys. The main goal is to see if a larger study is …