Catching up on sleep could rewire your metabolism, study finds
NCT ID NCT04214184
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at 38 adults who usually sleep less than 6 hours a night. Researchers helped them increase their sleep to the recommended 7 hours and measured changes in blood chemicals and insulin sensitivity. The goal was to find biological markers that can tell if someone is getting enough sleep.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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38 people
The number who actually took part.
- Started
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Dec 2019
- Finished
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Dec 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 35 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. 18-35 years old; men and women a. Equal numbers of women and men will be included. 2. Body Mass Index (BMI) of \> 18.5 and \<24.9. 3. Inactive to habitual moderate physical activity level (\<5 days of exercise per week). 4. Sleep/wake history: habitual sleep duration less than 6 hours per night. 5. Altitude history: Potential participants must have lived at Denver altitude or higher for at least 3 months. Exclusion Criteria: 1. Any clinically significant unstable medical or surgical condition within the last year (treated or untreated). 2. Any clinically significant psychiatric condition, as defined by DSM-IV-TR. I 3. Any clinically significant sleep disorder. 4. Use of prescription medications/supplements within one month or need of these medications at any time during the study. 5. Symptoms of active illness (e.g., fever). 6. Uncorrected visual impairment 7. History of shift work in prior year or travel more than one time zone in three weeks prior to study. 8. Participants must be entirely drug-free of illicit drugs, medications, nicotine and herbal products for one month prior to study. 9. Blood donation in the 30 days prior to inpatient study. 10. Ovulating women will be selected on the basis of a history of regular menstrual cycle ranging in length from 25-32 days with a maximum of three days variation month-to-month. They will have no history of prior gynecological pathology, be at least 1 year post-partum, not breast-feeding and not pregnant (HCG pregnancy test at screening and upon admission to the inpatient protocol).
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Sleep Wake Center--University of Utah
Salt Lake City, Utah, 84108, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Scientists put sleep loss under the brain scanner
- Magnetic pulses to the brain may help lung transplant patients sleep
- Magnetic pulses to the brain may help lung cancer patients sleep after surgery
- Magnetic pulses to the brain may help cancer patients sleep better
- Can a sleepless night rewire hunger and memory?
- Extra sleep may boost insulin sensitivity and cut heart risk