University Of Florida

This study tested whether a probiotic called Lactobacillus johnsonii N6.2 is safe and tolerable for adults with type 1 diabetes. Forty-six participants took either the probiotic or a placebo daily for 24 weeks, and researchers monitored their blood counts, metabolic panels, and a…

This study tested two ways to help people keep weight off after losing at least 5% of their body weight. One group got monthly phone calls, while the other got calls only when a computer algorithm predicted they were at high risk of regaining weight. The goal was to see which app…

This study tested whether a weight-loss medication (phentermine/topiramate) can help shrink kidney stones and improve health in obese adults with uric acid stones and type 2 diabetes or pre-diabetes. Nineteen participants were randomly assigned to either the drug or standard care…

This study tested a mobile health tool called AIM2ACT designed to help adolescents ages 12-15 with poorly controlled asthma better manage their condition. The tool was used alongside standard care to improve asthma control, measured by a questionnaire. The study involved 320 teen…

This study tested whether minocycline, an inexpensive antibiotic already approved for other uses, can lower blood pressure in people whose hypertension does not respond to standard medications. Researchers enrolled 34 adults with resistant hypertension and gave them different dos…

This study tested storing donor lungs at a cooler temperature (10°C) to allow transplant surgeries to be done during daytime hours instead of overnight. 45 people received lungs stored this way, and researchers checked how many had severe lung problems within 72 hours. The goal w…

This study looked at whether community health workers (CHWs) can help adults who have high blood pressure and struggle to afford enough food. 75 participants received support to eat more fruits and vegetables and manage their blood pressure. The goal was to see if this approach i…

This study tested an inhaled medication called treprostinil in 5 people with sarcoidosis who also have lung scarring and high blood pressure in the lungs. The goal was to see if the drug could improve blood flow and heart function. Participants took the drug and were monitored wi…

This study tested whether a virtual coach (through MyChart) helps people with obesity lose weight before ventral hernia surgery. Researchers compared weight loss over six months between those using the coach and those receiving usual care. The goal was to see if better pre-surger…

This study tested a probiotic called Lactobacillus johnsonii N6.2 in 30 children and adolescents with type 1 diabetes. The goal was to see if it is safe and could help preserve the body's ability to produce insulin by improving gut health and immune response. Participants took th…

This study looked at whether giving steroids twice a week (instead of daily) and adding exercise training could help boys with Duchenne muscular dystrophy (DMD) keep their muscle strength longer. The goal was to find a way to reduce side effects from daily steroids while still sl…

This study tested a mobile app called Family Fit to see if families liked using it and found it helpful. 30 parents and their children (ages 9-12) who were not very active used the app to encourage physical activity and prevent weight gain. The goal was to see if the app was easy…

This study tested whether giving warm, moist oxygen through a tracheostomy tube can prevent lung complications like pneumonia or collapsed lungs after major head and neck surgery. 56 adults who had surgery with a tracheostomy were randomly assigned to receive either this high-flo…

This study tested a 4.5-hour class program (spread over three weeks) to see if it could improve the health and wellness of healthcare providers, specifically bedside nurses. 31 nurses participated, filling out questionnaires and giving saliva samples before, one week after, and o…

This study looked at whether a nasal spray containing oxytocin, a natural hormone, can help reduce pain and improve daily function in older adults with knee osteoarthritis. Over 4 weeks, 83 participants used either the oxytocin spray or a placebo. The main goal was to measure cha…

This study tested a smartphone-based prayer program called PUSH (Pray Until Something Happens) to help adults with sickle cell disease reduce stress and pain. Forty participants who reported pain and used opioids were included. The goal was to see if adding prayer to standard car…

This study tested whether a program of friendly, supportive phone calls (called BE WITH) could help older adults feel less lonely, depressed, and isolated. Over 670 adults aged 55 and older who received meal services took part. Some received weekly calls for 8 weeks, while others…

This study tested whether drinking 100% orange juice every day for 12 weeks could protect women's skin from sun damage and improve overall skin health. Twenty women with fair to medium skin tones participated. Researchers measured skin redness after UV exposure and checked skin b…

This study tested a home-based digital exercise program to help older sepsis survivors improve their physical function. 21 participants were assigned to either the exercise program or standard care. The goal was to see if a remote program could be safe and effective for those who…

This study looked at whether a 12-week respiratory strength training program could improve swallowing and breathing in one person with Friedreich's ataxia. The participant had tests before and after training, including a camera look at swallowing, lung function measurements, and …

This study tested whether adding a special program focused on daily activities (like bathing and dressing) to usual home rehab helps older adults function better. 47 people aged 65+ with multiple health issues took part. The program aimed to improve motor skills and independence …

This study tested whether using nerve blocks with sedation instead of general anesthesia and opioids is safer and provides better pain control for high-risk patients needing an upper leg amputation. The study included 30 adults with conditions like diabetes, heart disease, or lun…

This study tested whether the antidepressant fluoxetine can reduce depression, anxiety, and other mental health issues in adults recovering from serious bone injuries requiring surgery. Over half of such patients develop lasting mental health problems. The trial enrolled 55 adult…

This study tested a group breathwork program for adults with chronic musculoskeletal pain (like back or neck pain lasting at least 3 months). 35 people participated to see if the program was practical, liked by patients, and could help reduce pain intensity and how much pain inte…

This study tested a special breathing program called Guided Respiration Mindfulness Therapy for adults with chronic low back pain. Nineteen people took part in 8 weekly one-hour breathing sessions. The goal was to see if the therapy was practical and liked by patients, and if it …

This study looked at whether a guided relaxation program on a tablet could help adults with sickle cell disease manage pain and stress while in the hospital. Forty-six participants used the program to listen to calming audio-visual recordings. The goal was to see if this simple, …

This pilot study tested whether taking krill oil supplements for 12 weeks could help older adults (60+) with chronic hip, knee, or lower back pain and mobility issues. The main goal was to see if people would stick with the supplement routine. Results will guide future larger stu…

This study looked at whether different breast pump suction patterns help mothers of critically ill infants produce more milk. 96 mothers who needed to use a breast pump exclusively for the first 14 days after giving birth took part. Researchers measured daily milk volume and aske…

This study tested whether a discreet, hands-free wearable breast pump could help Black mothers of critically ill infants in the NICU pump more often and produce more breast milk. Forty Black mothers were randomly assigned to use either the wearable pump with a tracking app or a s…

This small study tested whether breathing low-oxygen air in short bursts (acute intermittent hypoxia) can boost the brain's ability to improve swallowing safety in people with chronic mild-to-moderate traumatic brain injury. Five adults completed the study, which compared the low…

This study tested whether personalized text message reminders could help mothers of critically ill infants pump more breast milk. 122 mothers with babies in the NICU who planned to provide breast milk participated. Researchers sent real-time biomarker-based texts to encourage pum…

This study tested whether a nerve block (an injection near a nerve cluster in the face) can reduce pain and the need for strong painkillers after nose surgery. 50 adults having septorhinoplasty (surgery to fix a deviated septum and reshape the nose) took part. The approach aims t…

This study tested whether adding calcium to the standard oral rehydration solution (ORS) can reduce the severity of acute watery diarrhea in adults. 396 adults with diarrhea (some with cholera) took part. The goal was to see if the calcium-enriched drink decreases stool output an…

This study looked at whether a 12-week supervised aerobic exercise program can help mid-life adults with opioid use disorder feel less pain and move better. Only 6 people took part, so the main goal was to see if such a program is possible to run. The results will help design lar…

This study looked at how sensory-based treatments change the brains of children with autism spectrum disorder. Researchers used MRI scans and behavioral tests to see which treatments work best for different children. The goal was to learn how to personalize therapy for each child…

This study looked at whether the way a healthcare worker advances a catheter off the needle during IV insertion changes how much the needle tip moves. 80 experienced volunteers inserted IVs into a simulator using three different techniques. The goal was to find which method cause…

This study looked at gut tissue from 35 people with and without high blood pressure to see if there are differences in gut cells. Researchers used samples taken during routine colonoscopies and grew mini-guts in the lab to compare gene activity and growth. The goal was to underst…

This study looked at whether a dietary fiber from baker's yeast (beta-glucan) can improve how well the flu vaccine works in healthy adults aged 50 and older. 78 participants took either the supplement or a placebo before getting their flu shot. Researchers measured antibody level…

This study looked at whether a single dose of methylphenidate (Ritalin) changes how young adults with both ADHD and alcohol use disorder respond to pictures of alcohol. Using brain scans and tests, researchers measured cravings and attention. The goal was to understand the link b…

This study tested a new service that lets parents call for medical help at night and get medicine delivered to their home. The goal was to see if this approach could safely treat common childhood illnesses like pneumonia and diarrhea before they become emergencies. Over 1,200 chi…

This study tested whether a virtual coach can teach a life-saving emergency procedure as well as a human instructor. Fourteen adults used a mixed-reality simulator to learn how to insert a balloon into the aorta to stop severe bleeding. The goal was to see if the virtual coach wa…

This study aimed to find a way to measure frataxin mRNA in blood and spinal fluid from 10 adults with Friedreich's ataxia. Researchers used tiny particles called exosomes to detect the mRNA. If successful, this could become a tool to monitor treatments that aim to boost frataxin …

This study looked at how sleep affects balance and thinking in healthy adults aged 65 and older. Over six weeks, 18 participants wore an OURA ring and kept a sleep diary while doing balance and memory tests. The goal was to understand daily connections between sleep, mobility, an…

This study measured brain signals in 21 people with essential tremor or Parkinson's disease during deep brain stimulation (DBS) surgery. The goal was to understand how the brain's motor network produces tremor. The findings may help improve future treatments, but this study did n…

This study tested a computer tool designed to help doctors and patients make shared decisions about chronic pain treatment. 39 adults with long-term muscle or bone pain who had recently used opioids took part. The goal was to see if clinics would use the tool and if it improved c…

This study looked at how well clear aligners can rotate canine teeth. It compared using special attachments, a technique called IPR (slightly reshaping the tooth surface), or both. 80 adults with rotated canines took part. The goal was to see which method gives the most accurate …

This study tested a digital conversation aid to help patients and doctors make shared decisions about thyroid biopsy. Researchers enrolled 107 adults with thyroid nodules to see if using the tool during clinic visits was practical. The goal was to gather information for a future …

This study looked at how limiting eating to certain hours of the day (time-restricted eating) affects energy use and daily body rhythms in overweight adults aged 65 and older. Fifteen participants wore activity and sleep trackers, had blood tests, and used continuous glucose moni…

This study followed 378 people with moderate-to-severe dementia with Lewy bodies (DLB) and their caregivers for up to three years. Researchers tracked symptoms, quality of life, and caregiver experiences to find clues that death may be near within six months. The goal is to help …

This study looked at how a very low-carb ketogenic diet compares to a Mediterranean diet for bone health and muscle function in older adults. Twelve postmenopausal men and women participated in this short-term pilot trial. The goal was to gather initial data on safety and benefit…

This study tested if wearing Invisalign aligners for only 3 days (instead of the usual 7) could still move teeth as planned. Forty adults with mild crowding participated. Researchers compared tooth movement accuracy and speed between the two wear schedules to see if a shorter wea…

This study tested whether a newer ultrasound method (biplane) helps doctors perform epidural injections in children more effectively than the standard single-plane method. It involved 46 boys aged 4 months to 10 years undergoing circumcision. The goal was to see if biplane ultras…

This study followed 53 ICU patients who had a serious abdominal infection to understand why many become weak, frail, and disabled long after leaving the hospital. Researchers measured changes in frailty, muscle loss, and overall health at 3, 6, and 12 months. The goal was to defi…

This small pilot study looked at whether drinking beet juice could improve blood vessel and breathing muscle function in older adults with coronary artery disease. Eight participants were given either nitrate-rich beet juice or a placebo to see if the study design was feasible an…