University Of Florida

This study tests whether ivermectin, a cheap drug used for parasites, can safely boost the effects of standard immunotherapy in adults with solid tumors. Researchers will give ivermectin alongside ongoing immune checkpoint inhibitor therapy to 80 participants. The goal is to see …

This early-phase study tests a new treatment for children and young adults with aggressive brain tumors called high-grade glioma and DIPG. The therapy uses the patient's own immune cells, modified to better find and attack the tumor. The main goals are to see if the treatment is …

This study tests whether an artificial intelligence (AI) system can help doctors choose the best doses of anti-rejection drugs for kidney transplant patients. The goal is to reduce kidney scarring and protect the new kidney's function over time. About 34 adults who have received …

This early-phase study tests a new treatment for adults whose cancer has spread to the brain. The therapy uses a patient's own immune cells, modified to better target and attack tumor cells. The main goals are to see if the treatment is safe and possible to give, with 12 particip…

This early study tests whether a special brain pacemaker (adaptive deep brain stimulation) can safely help people with spinocerebellar ataxia type 6, a rare disease that causes balance and coordination problems. Five adults will have electrodes placed in the cerebellum to record …

This study will test a computer program that helps emergency room doctors spot patients who may have hepatitis C or HIV without knowing it. The tool uses patient data to suggest who should be tested. Researchers will compare this targeted approach to current screening methods to …

This study tests a behavioral program for men who use stimulants like meth or cocaine and are at high risk for HIV. The goal is to help them start taking PrEP (a daily pill that prevents HIV) and reduce their drug use. About 84 participants will be enrolled to see if the program …

This study tests a program called PINPOINT that helps women with obesity or diabetes get screened for cervical cancer. About 20 women who are overdue for screening will try the program, which offers options like self-collection for HPV testing. The goal is to see if the program i…

This study tests if digital videos for new mothers can help prevent obesity in babies during their first year. About 50 mothers in a home visiting program will watch short videos on feeding, activity, and sleep. Researchers will check the babies' weight and ask mothers about thei…

This study tests whether doing breathing muscle exercises at home for at least two weeks before breast cancer surgery can prevent the breathing weakness that often happens after surgery. Forty newly diagnosed adults will either do these breathing exercises or guided imagery exerc…

This study tests whether a 5-week virtual cognitive training program works as well as an 8-week version for people aged 65+ with mild cognitive impairment (MCI). Participants will attend weekly group sessions online and complete memory tests and questionnaires. The goal is to imp…

This study tests whether a special flickering light and sound therapy, done three times a week for three months, can improve thinking, walking, balance, and mood in healthy older adults and those with mild memory worries. Researchers will also check if the therapy slows brain shr…

This early-phase study tests whether AB-free kava can improve mobility and physical function in adults over 70 who have trouble sleeping and are somewhat inactive. About 40 participants will take either the kava supplement or a placebo for a short time. Researchers will measure w…

This study tests a brain stimulation technique called TMS to help female athletes who have both depression and a concussion. About 35 women aged 18-65 will receive the treatment to see if it eases their symptoms. The goal is to improve mood and concussion recovery without medicat…

This study tests if combining light therapy (photobiomodulation) with a topical pain gel (diclofenac) can reduce pain and inflammation in people with knee osteoarthritis. About 32 adults aged 50 and older with chronic knee pain will receive the treatments and be followed for one …

This study tests whether a smartphone app called the Cancer Exercise app (CEA) can help cancer survivors become more physically active. 750 adults who have finished cancer treatment will either use the app for 12 weeks or receive usual care. The goal is to see if the app increase…

This study tests whether a non-invasive ear stimulation device (tVNS) can reduce stress during performance tasks like public speaking. About 200 healthy adults will be randomly assigned to receive active or placebo stimulation while preparing a speech or doing a writing task. Res…

This study tests whether combining a non-invasive brain stimulation technique (rTMS) with walking and eye-movement exercises can improve balance and walking in people with mild cognitive impairment. Researchers will enroll 30 adults aged 18-80 to see if the approach is feasible a…

This study looks at whether a single dose of methylphenidate (Ritalin) changes how the brain responds to alcohol-related images in young adults aged 18-25 with alcohol use disorder. Participants will have brain scans and complete tasks after taking either the drug or a placebo. T…

This study looks at whether a four-session web program can help romantic partners of people who drink heavily. About 160 couples will take part, answering surveys and tracking their feelings and communication for 21 days. The goal is to see if the program reduces the partner's de…

This study will give parents special thermoses designed to keep breastmilk at a safe temperature for over 15 hours. Parents and daycare providers will use each thermos for four weeks and report any problems. Researchers will also check the milk temperature daily to make sure it s…

This study will test an expanded version of the uSafeUS mobile app, designed to help college students drink less and lower their risk of sexual assault. About 90 students aged 18-25 will use the app for one month and complete surveys. The goal is to see if students find the app u…