Ain Shams University

This study tests whether a manuka honey mouthwash can improve gum health in people with kidney failure who are on dialysis. Gum disease is very common in these patients and can lead to tooth loss and inflammation. The trial will compare the honey rinse against standard care in 15…

This study tests whether a heart medication called nebivolol can prevent heart damage caused by trastuzumab, a common breast cancer drug. About 56 adults with HER2-positive breast cancer will take nebivolol or a placebo during their cancer treatment. The goal is to see if nebivol…

This study aims to find the best treatment approach for children and teens with orbital lymphatic malformation, a rare eye condition. Researchers will test the safety and effectiveness of the drug sirolimus, with or without injection therapy, in 30 participants aged 1-18. The goa…

This study tests whether alpha lipoic acid, a common antioxidant supplement, can prevent or lessen skin irritation caused by radiation therapy in breast cancer patients. Forty women scheduled for radiation will take the supplement and be monitored for skin reactions and inflammat…

This study compares two methods to manage pain after hip surgery: a fascia iliaca block (an injection near the hip nerves) and intrathecal nalbuphine (a painkiller given with spinal anesthesia). The goal is to see which approach keeps patients comfortable longer after surgery. Th…

This study compares two medicines, hydrocortisone and dexmedetomidine, to see which works better at preventing shivering after abdominal surgery with general anesthesia. About 70 adults having abdominal surgery will take part. The goal is to find a more effective way to keep pati…

This study tests a new way to deliver steroid injections for long-term leg pain caused by nerve issues. It compares the new 'transgrade' method to the standard 'interlaminar' approach. 80 adults with pain lasting over 6 months will be treated and followed for 3 months to see whic…

This study compares two ultrasound-guided nerve block methods for adults having surgery on the lower arm or hand. The goal is to see which approach numbs the arm faster. Fifty participants will be randomly assigned to one of the two techniques.

This study tests whether itopride, a drug that helps move food through the stomach, can reduce the risk of food or liquid remaining in the stomach after fasting in people taking semaglutide (a diabetes medication). 60 diabetic patients scheduled for hysterectomy will receive eith…

This study tests whether high-level laser therapy can treat oral mucositis (painful mouth sores) in children under 18 who are getting a bone marrow transplant. Fourteen participants will receive laser treatment on their sores, and researchers will measure sore severity and pain l…

This study looks at whether adding nitrates (found in foods like beets) to a standard pre-surgery carbohydrate drink can help women recover faster after open gynecological surgery. The goal is to reduce the length of hospital stay by easing the body's stress response to surgery. …

This study tests whether a lidocaine nasal spray can reduce pain and the need for strong opioid drugs during partial turbinectomy (nose) surgery. Researchers will enroll 50 adults undergoing this surgery. The goal is to see if the spray helps patients recover faster and with less…

This study compares how quickly people can bite and release when wearing a lower denture held in place by either two regular-sized implants or four smaller mini-implants. Researchers will measure chewing timing and denture stability in 28 adults with no lower teeth. The goal is t…

This study tests whether giving ketamine before laparoscopic sleeve gastrectomy (a type of weight-loss surgery) can reduce pain after the operation. Researchers will compare how long it takes for patients to need extra pain medicine. The study includes 90 adults with a BMI betwee…

This study compares two types of nerve blocks (ESPB and SAPB) to see which one controls pain better after video-assisted lung surgery. About 50 adults aged 25-70 will take part. The goal is to find the best way to reduce pain after surgery.

This study compares a new 3D-printed dental expander with the traditional one for widening the upper jaw in teenagers aged 12 to 17. The goal is to see which device works better and fits more precisely using 3D imaging. The trial involves 22 participants and aims to improve treat…

This study will use ultrasound to track changes in muscle, fat, and fluid levels in critically ill pregnant and gynecological patients. Researchers want to see if these body changes are linked to serious outcomes like death, need for a breathing machine, or longer ICU stays. Abou…

This study looks at whether a quick ultrasound scan before surgery can predict if a patient's blood pressure will drop dangerously after they are put to sleep for brain surgery. Researchers will measure the size of a large vein and an artery in the belly. 36 adults having planned…

This study tests two ways to place dental implants: one uses a custom-made physical guide, the other uses a computer screen to show the dentist where to drill in real time. Twenty healthy adults with a missing upper tooth will take part. The goal is to see which method is more ac…

This study looks at whether certain blood test results can help predict how well sepsis patients in the intensive care unit will do. Researchers will compare three different markers in the blood to see which one best forecasts the risk of death within 28 days. The goal is to find…

This study looks at how two different anesthetic gases, isoflurane and sevoflurane, affect oxidative stress (a type of cell damage) in 80 adults having their gallbladder removed by keyhole surgery. The goal is to see which gas causes less stress and inflammation in the body. Part…

This study looks at whether a quick breathing measurement called the Rapid Shallow Breathing Index (RSBI) can accurately predict when a patient in the intensive care unit (ICU) is ready to have their breathing tube removed. Researchers will measure RSBI in 70 adult patients who a…

This study checks if a simple blood test (D-dimer) can help predict how serious pneumonia is and how well patients will recover. Researchers will measure D-dimer levels in 50 adults with pneumonia and compare them to a standard severity score. The goal is to see if high D-dimer l…

This study looks at whether a simple bedside lung ultrasound can help find lung issues early in women who are critically ill due to pregnancy complications or gynecologic cancer. Researchers will check 64 patients in the intensive care unit for different lung ultrasound patterns …

This study looks at 100 people having laparoscopic weight-loss surgery. At the end of surgery, doctors will use one of two methods to reopen the lungs. The goal is to find out which method is safer and better at helping patients breathe after surgery.

This study compares three different single-use flexible ureteroscopes used to remove kidney stones. Researchers will measure which scope is most cost-effective, how long surgery takes, how many stones are completely removed, and how many complications occur. The trial will enroll…