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Neck ultrasound may predict anesthesia danger in liver patients

NCT ID NCT07370103

Knowledge-focused Sponsor: Ain Shams University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether a simple neck ultrasound can predict dangerous drops in blood pressure after anesthesia in adults with chronic liver disease. Researchers will measure blood flow in the carotid artery before and after anesthesia in 35 patients. If the method works, it could help doctors prevent complications during surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could give doctors a simple, non-invasive way to predict dangerous drops in blood pressure during anesthesia in patients with chronic liver disease.
What could go wrong
This is a small, early-stage study with only 35 participants. The ultrasound method may not be accurate enough to replace standard monitoring, and results may not apply to all liver disease patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 35 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Apr 2026

An estimate. Start dates often move.

Expected to finish

Apr 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

* Adult patients (≥ 18 years) with a confirmed diagnosis of CLD (e.g., cirrhosis, non-alcoholic steatohepatitis) * scheduled for elective surgery under general anesthesia. * ASA 2,3,4 * ASA 4 patients will be included only if their baseline MAP is \>65 mmHg, as per the exclusion criteria

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * • Adult patients (≥ 18 years) with a confirmed diagnosis of CLD (e.g., cirrhosis, non-alcoholic steatohepatitis) * scheduled for elective surgery under general anesthesia. * ASA 2,3,4 * ASA 4 patients will be included only if their baseline MAP is \>65 mmHg, as per the exclusion criteria Exclusion Criteria: * • Refusal to participate * Patients with known cardiac disease (e.g., severe valvular disease, congestive heart failure), * pre-existing severe hypotension (e.g., mean arterial pressure \<65 mmHg * emergency surgery * anatomical variations preventing adequate ultrasound visualization of the carotid artery. * Carotid artery stenosis. * Mean arterial pressure (MAP) \> 120 mmHg before anesthesia * any previous record of neck surgery or trauma. * acute renal injury. * oral angiotensin receptor blockers or angiotensin-converting enzyme inhibitors (ACEI) * lateral, prone, and lithotomy operations * body mass index (BMI) \> 30 kg/m2 or \< 15 kg/m2

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Conditions

The condition(s) this trial relates to.

liver disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Hypotension on induction

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

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Contacts and locations

Locations

  • Ainshams University

    RECRUITING

    Cairo, Egypt

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