Ain Shams University

This study tests whether adding a microfracture procedure to standard meniscus repair improves knee function and healing. Thirty adults with isolated meniscus tears will be randomly assigned to receive either repair alone or repair plus microfracture. Researchers will measure out…

This study compares two ways of making dental onlays (custom caps for damaged molars): milling from a solid block versus 3D printing. Thirty adults with decayed, broken, or poorly filled molars will receive either type of onlay. Researchers will check how well the onlays fit and …

This study tests whether a daily dose of alpha lipoic acid, an antioxidant supplement, can lower the risk of heart problems in 50 children who are on regular hemodialysis. Participants will either take the supplement or a placebo pill for a period, and researchers will monitor fo…

This study tests whether dexmedetomidine, a sedative, can reduce acute kidney injury in 78 adults undergoing ascending aortic surgery with a heart-lung machine. The drug may protect kidneys by calming inflammation and stress. Researchers will compare kidney function and side effe…

This study looks at whether dulaglutide, a drug used for type 2 diabetes, can help regulate menstrual cycles in adolescent girls with type 1 diabetes who have poor blood sugar control. Researchers will give some participants dulaglutide plus insulin, while others get only insulin…

This study tests two different varnishes to treat white spot lesions—early signs of tooth decay—in people aged 15 to 25. Each participant gets one varnish on one side of their mouth and the other varnish on the opposite side. The goal is to see which varnish better restores tooth…

This study looks at whether a strong antibiotic called meropenem (a carbapenem) works better than another antibiotic called piperacillin/tazobactam for treating sepsis in burn patients. Sepsis is a life-threatening infection that can happen after severe burns. The study will trac…

This study tests three different medicines for treating infected baby molars in children aged 4-8. The goal is to see which works best to stop pain, swelling, and infection. Researchers will also check how well each medicine kills bacteria in the lab.

This study tests a less invasive way to treat receding gums using a collagen membrane instead of a tissue graft. Eighteen healthy adults with localized gum recession will receive one of two treatments. The goal is to see if the collagen membrane works as well as the standard graf…

This study looked at whether giving N-acetyl cysteine (NAC) and vitamin D, along with standard care, can help children who swallowed a corrosive substance. The main goal was to see if these treatments could prevent narrowing of the food pipe (strictures) and speed up recovery. Ei…

This study looks at whether giving extra sodium (salt) to premature babies starting at least one week after birth helps them gain weight and grow better. The trial includes 74 preterm infants with low birth weight. Researchers will track their weight for six weeks and check for s…

This study tests three special materials used to treat deep cavities in children's permanent molars that are still growing. The goal is to keep the tooth alive and allow the root to finish forming normally. Sixty-nine children aged 7 to 10 will receive one of the three materials …

This study compares total intravenous anesthesia (TIVA) to balanced anesthesia (using inhaled gas) in 60 diabetic patients undergoing video-assisted chest surgery. The goal is to see which method better controls blood sugar and reduces stress during surgery. Researchers will also…

This study compares two types of nerve blocks (retrolaminar block vs. serratus anterior plane block) to see which provides better pain relief after radical mastectomy. About 90 women aged 25-65 undergoing breast cancer surgery will receive one of the blocks before general anesthe…

This study looks at two ways to treat a painful tooth infection: vital pulp therapy (saving the nerve) and standard root canal (removing the nerve). About 34 adults with deep cavities and tooth pain will get one of these treatments. The goal is to see which method causes less pai…

This study tests whether adding ketamine to dexmedetomidine sedation improves comfort and brain signal quality during awake deep brain stimulation (DBS) surgery for movement disorders like Parkinson's disease. About 24 adults will be randomly assigned to receive either the combin…

This study compares two procedures to relieve chronic tailbone pain (coccydynia) that is not related to cancer. About 74 adults aged 20-70 who have not responded to standard medical treatment will be split into two groups. One group will receive conventional radiofrequency ablati…

This study tests whether adding dexamethasone or dexmedetomidine to a standard numbing medicine (bupivacaine) can provide longer pain relief after rhinoplasty (nose job). 90 adults having nose surgery will receive one of these combinations as a nerve block. The main goal is to se…

This study looks at whether sugammadex, a drug used to reverse muscle relaxants, can lower the chance of agitation when adults wake up from nasal surgery. About 486 adults aged 18 to 60 having procedures like septoplasty or sinus surgery will be observed. The goal is to see if th…

This study compares two types of nerve blocks (RISS and QL) to see which provides better pain relief after open kidney removal. Fifty adults aged 40-70 having open nephrectomy will receive one of the two blocks. The main goal is to see how long it takes before they need additiona…

This study tests whether a special oxygen gel applied to stitches after oral surgery can improve wound healing and reduce bacteria. About 44 healthy adults who need dental surgery will receive either the oxygen gel or standard care. Researchers will check healing at 1 and 2 weeks…

This study tests whether a smartphone-based AI tool can help doctors give a pain-blocking injection to babies having cleft lip repair. The goal is to reduce pain during surgery and the need for extra pain medicine. The study includes 120 infants aged 5-18 months and compares the …

This study compares two types of nerve blocks (ESPB and QLB) for pain control after lower back surgery. Forty adults aged 18-65 will receive one of the two blocks, and researchers will measure pain levels using a simple 0-10 scale. The goal is to find which block provides better …

This study tests whether making small holes in the jawbone (micro-osteoperforations) helps clear aligners straighten crowded lower front teeth faster. Twenty adults with mild crowding will be treated with aligners, with half also getting the bone procedure. Researchers will compa…

This study looks at whether a numbing injection near the neck (superficial cervical plexus block) can reduce pain after ear surgery. About 46 adults aged 20-40 will either get the block plus general anesthesia or just general anesthesia. The goal is to see if the block lowers pai…

This study looks at whether using 3 screws instead of 4 to attach a full lower-jaw dental bridge affects bone loss around the implants. Fourteen men with no teeth in their lower jaw and no major health issues are being followed with X-rays over time. The goal is to see if fewer s…

This study compares total intravenous anesthesia (using propofol and dexmedetomidine) to inhalational anesthesia (using sevoflurane) in 40 adults undergoing inguinal hernia repair. Researchers measure inflammatory markers in the blood before and after surgery, along with hospital…

This study is looking at whether changes in a blood protein called albumin can predict how well ICU patients with sepsis will do, compared to the usual test for lactic acid. Researchers will track 40 non-surgical ICU patients to see which marker better predicts recovery or death.…

This study follows 100 head and neck cancer patients before and after radiotherapy to see how it changes their teeth, gums, and saliva over time. Researchers measure gum attachment, pocket depth, and bleeding to understand long-term oral health effects. The goal is to help doctor…

This study looks at whether using a second sperm sample from the same man can lead to better fertilization and embryo development during ICSI (a type of IVF). It involves 108 couples where the male partner has abnormal sperm. The goal is to see if the second sample has more healt…

This study looks at how kangaroo mother care (skin-to-skin contact) affects energy use in preterm babies born at 32-36 weeks. Researchers will measure urine markers of energy and stress, along with heart rate, breathing, and temperature. The goal is to understand if this simple, …

This study looks at 37 children with acute respiratory distress syndrome (ARDS) who are on breathing machines. Researchers want to see if measuring certain inflammation markers in saliva works as well as measuring them in fluid from the lungs. If saliva works, it could lead to a …

This study looks at how head and neck position (sniffing vs. ramped) and the type of blade used on a video laryngoscope affect how quickly a breathing tube can be placed in 140 severely obese patients (BMI 40 or higher) undergoing elective surgery. The goal is to find the best co…

This study compares two ways to predict if placing a breathing tube in a child will be difficult: an ultrasound of the airway versus a standard physical exam. Researchers will watch 130 children having planned surgery to see which method works better. The goal is to improve safet…

This study looks at how two types of occlusal veneers (thin covers for back teeth) hold up under different biting forces. Researchers will use computer simulations and check the veneers in 8 adults aged 25-35 with certain cavities. The goal is to see which veneer type resists wea…