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New sedation combo may improve awake brain surgery experience

NCT ID NCT07513935

First seen Apr 23, 2026 · Last updated Jun 17, 2026 · Updated 10 times

Summary

This study tests whether adding ketamine to dexmedetomidine sedation improves comfort and brain signal quality during awake deep brain stimulation (DBS) surgery for movement disorders like Parkinson's disease. About 24 adults will be randomly assigned to receive either the combination or dexmedetomidine alone. The goal is to find a safer, more effective sedation approach that keeps patients calm yet responsive during the procedure.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Ainshams University

    Cairo, Egypt

Conditions

The condition(s) this trial relates to.

essential tremor Intraoperative Awareness Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.