Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Anesthesia showdown: which method calms inflammation after hernia surgery?

NCT ID NCT07271459

Knowledge-focused Sponsor: Ain Shams University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Sep 17, 2026 · Updated 2 times

Summary

This study compares total intravenous anesthesia (using propofol and dexmedetomidine) to inhalational anesthesia (using sevoflurane) in 40 adults undergoing inguinal hernia repair. Researchers measure inflammatory markers in the blood before and after surgery, along with hospital stay length and nausea/vomiting. The goal is to see which anesthesia method leads to less inflammation and a smoother recovery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
propofol, dexmedetomidine, sevoflurane
What this could lead to
If it works, this could help doctors choose anesthesia that reduces inflammation and speeds recovery after hernia surgery.
What could go wrong
This is a small, early-phase study with only 40 participants, so results may not apply to everyone. It measures blood markers, not long-term outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

40 people

The number who actually took part.

Started

Feb 2026

Expected to finish

Oct 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 50 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Adult patients between 18 and 50 years of age undergoing elective inguinal hernia repair. 2. American Society of Anesthesiologists physical status classification (ASA) I and II. Exclusion Criteria: 1. Patient's refusal. 2. ASA \> II 3. Complicated hernia. 4. Previous hernia repair with mesh. 5. History of allergy to any of the study drugs. 6. History of any heart disease affecting cardiac function or rhythm or receiving medications that decrease the heart rate (HR). 7. Baseline HR≤60 beat/min. 8. Baseline mean arterial pressure (MAP)≤70 mmHg. 9. Psychiatric illness. 10. Patients with chronic kidney or liver disease. (Creatinine clearance\<50 mL/min or serum albumin level\<2g/dL.) 11. Patients with immunological disorders or receiving immunosuppressive treatment or anti-inflammatory drugs. 12. Patients with neoplasms, chronic inflammatory states, or active infections. 13. Patients with any type of anemia or those who received iron therapy or blood transfusion within 4 weeks.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Anesthesia are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anesthesia

Contacts and locations

Locations

  • Ain Shams University Hospitals

    Cairo, Cairo Governorate, Egypt

More trials for these conditions

Other studies related to the condition(s) this trial covers.