Could a different anesthesia method help diabetics during surgery?
NCT ID NCT07496593
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares total intravenous anesthesia (TIVA) to balanced anesthesia (using inhaled gas) in 60 diabetic patients undergoing video-assisted chest surgery. The goal is to see which method better controls blood sugar and reduces stress during surgery. Researchers will also monitor side effects like nausea, vomiting, and pain after surgery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Propofol, fentanyl, atracurium (TIVA) vs isoflurane and atracurium (balanced anesthesia)
- What this could lead to
- If TIVA works better, it could lead to safer anesthesia for diabetic patients, with better blood sugar control and fewer complications during chest surgery.
- What could go wrong
- This is a small, single-center study with only 60 participants. Results may not apply to all diabetic patients or surgeries, and the benefit may be small.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Phase 4
Runs after approval, following long-term safety and how well the treatment works in everyday use.
- Participants
-
60 people
The number who actually took part.
- Started
-
Dec 2025
- Expected to finish
-
Dec 2026
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 70 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patient for both sex scheduled for VATS. * Age group 18-70 years. * Diagnosed diabetes mellitus (Type 1 or 2) HbA1c 6-8 % within 3 months. * ASA II and III. Exclusion Criteria: * HbA1c \> 8 % or \< 6 or preoperative insulin infusion or DKA within 3 months * Emergency surgery. * Drug allergy. * Chronic high-dose steroids. * Severe hepatic/ renal impairment, significant arrhythmia or severe LV dysfunction. * Patient refusal. * Psychiatric illness.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Ain Shams University
Cairo, Abasya, Egypt
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