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3D-Printed tooth restorations face off against milled ones in new trial

NCT ID NCT05943782

Disease control Sponsor: Ain Shams University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only This study
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two ways of making dental onlays (custom tooth restorations) for damaged molars: milling from a solid block versus 3D printing. Thirty adults with cavities, broken teeth, or old fillings will receive either a milled or 3D-printed onlay. Researchers will check how well the onlays fit and function over one year using digital scans and clinical exams.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
dental onlay (milled or 3D-printed ceramic restoration)
What this could lead to
If successful, this could show that 3D-printed onlays are as good as milled ones, offering a faster or cheaper option for dental restorations.
What could go wrong
This is a small, early-stage trial with only 30 participants, so results may not apply to everyone. The study focuses on short-term fit and function, not long-term durability.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 30 people

The number the study aims to enrol. It can still change while the study runs.

Started

Sep 2024

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 50 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Presence of caries lesion, defective amalgam, or composite restorations in posterior dentition (molars), suitable for the restoration with ceramic onlays. 2. Presence of antagonist tooth. 3. Adult patients (age: 18-50 years) of both genders. 4. Good general and oral health; Able to tolerate necessary restorative procedures and willing to sign an informed consent. 5. Absence of orthodontic appliances. 6. Absence of malocclusion and tooth malformation. Exclusion Criteria: 1. Presence of non-carious cervical lesions. 2. Pregnant women. 3. Allergy to any of the restorative materials. 4. Mobile teeth, indicating periodontal disease or trauma. 5. External or internal resorption.

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Conditions

The condition(s) this trial relates to.

dental caries tooth disorder Tooth Fractures

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Broken teeth Caries,dental Defective dentition Fracture tooth

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • AinShams university

    Cairo, 11263, Egypt

More trials for these conditions

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