INFERTILITY

This study is testing whether a medication called atosiban can help women with a history of failed IVF attempts have a successful pregnancy. Researchers will give atosiban or a placebo (inactive solution) to about 800 women right before a single embryo transfer to see if it impro…

This study is testing whether taking the fertility drug letrozole for 10 days works better than the standard 5-day course for women with PCOS who are trying to get pregnant. Researchers will compare how often ovulation and pregnancy occur in each group. The goal is to find the mo…

This study compares a generic version of a fertility medication against the original brand-name version for women undergoing IVF treatment. Researchers want to see if the less expensive generic drug works just as well at helping women achieve live births. The trial involves over …

This study is testing whether taking the weight-loss medication semaglutide for 12 weeks before IVF treatment can improve the quality of embryos for overweight and obese women. Researchers will compare women who receive the drug to those who do not, focusing on the number of high…

This study is testing whether growth hormone or DHEA supplements can help women with poor ovarian reserve produce more eggs during IVF treatment. Researchers will compare which supplement works better at increasing the number and size of egg follicles. The study involves 165 wome…

This study is testing whether adding a hormone called recombinant LH to the standard fertility medication (FSH) improves outcomes for women over 35 who had a lower-than-expected number of eggs retrieved in a previous IVF cycle. The goal is to see if this personalized approach lea…

This study is testing whether using a thicker, hyaluronic acid-rich solution during embryo transfer leads to more live births compared to a standard solution. It involves 858 women undergoing single embryo transfer as part of fertility treatment. Participants are randomly assigne…

This study is testing whether a new formulation of vaginal progesterone works as well as the standard version for supporting early pregnancy during frozen embryo transfers. The trial involves 1,020 women undergoing fertility treatment, comparing pregnancy rates between two differ…

This study observes how REKOVELLE, a fertility medication, works in real-world practice for Chinese women undergoing IVF or ICSI treatments. Researchers will follow 2,500 women across China to see how the drug affects pregnancy rates, safety, and treatment patterns. The study doe…

This study is for women undergoing IVF who are expected to have a lower number of eggs. It compares two different medication doses used to stimulate the ovaries. Researchers want to see if a lower, milder dose produces better quality embryos than a higher, more intense dose. The …

This study aims to find out if having complete surgery to remove colorectal endometriosis before starting IVF treatment leads to better pregnancy rates compared to starting IVF treatment alone. It will involve 120 women with this specific type of endometriosis who are struggling …

This study is testing a laboratory technique to help eggs and sperm from couples with infertility successfully fertilize. It is for people who have had complete fertilization failure during standard IVF or one failed ICSI treatment cycle. The goal is to see if treating the eggs a…

This study is testing a specific, fixed dose of a fertility hormone (Rekovelle) for women undergoing a common fertility procedure called intrauterine insemination (IUI). The goal is to help the ovaries produce the ideal number of eggs—aiming for two—to increase the chance of preg…

This study is testing whether using new devices to make the embryo transfer step of IVF more consistent can lead to more successful pregnancies. It will compare standard manual transfer to transfers assisted by devices that keep the embryo at a stable temperature and control the …

This study aims to see if blood-thinning medications, which are sometimes given to women with infertility, actually help the womb prepare for pregnancy. Researchers will use special ultrasound scans to closely examine the womb lining in about 300 women. They will compare the scan…

This study is testing whether a new combination of two fertility hormones works better and is as safe as the standard treatment for Japanese women who lack specific hormones needed for egg development. About 333 women who need help getting pregnant through IVF will receive either…

This study is testing whether changing the timing of a common fertility treatment can help more people have babies. Researchers want to see if waiting 42 hours instead of 36 hours after an ovulation trigger shot improves live birth rates during intrauterine insemination (IUI). Th…

This study is looking at whether a common thyroid medication helps women with a mild thyroid condition have better outcomes with IVF. It will compare women who take the medication to those who don't, tracking key results like pregnancy and live birth rates. The goal is to see if …

This study is testing a new herbal medicine formula called Melats P to see if it can help women with Polycystic Ovary Syndrome (PCOS). Researchers want to find out if this natural treatment can safely regulate menstrual cycles, improve hormone levels, and help with fertility. The…

This study offers an experimental procedure to freeze and store testicular tissue from boys (ages 0-17) who are about to undergo cancer treatments like chemotherapy or radiation that have a high risk of causing permanent infertility. The goal is to preserve the tissue so it might…

This study is testing whether smelling lavender essential oil can help improve mental health and quality of life for women waiting to undergo IVF treatment. 120 women will be randomly assigned to use real lavender oil, a fake lavender scent, or receive their usual care for four w…

This study is testing if using warmed dye instead of cold dye during a standard fertility test (HSG) makes the procedure less painful and reduces false readings of blocked fallopian tubes. It will involve 240 women aged 18-45 who need this test as part of their fertility evaluati…

This study is testing whether a sedative called remimazolam, when used with a painkiller, is safer than the current standard sedative during IVF egg retrieval. It aims to reduce episodes of low oxygen levels (hypoxia), which is a common risk during this procedure. Researchers wil…

This study aims to find out which of two common vaginal progesterone treatments is more comfortable and convenient for women undergoing frozen embryo transfer (FET). It will involve 400 women who will use either soft capsules or pessaries and report on their experience. The resea…

This study aims to understand how infertility and fertility treatments affect women's sexual function and behavior. Researchers will ask 500 women undergoing fertility treatment to complete anonymous questionnaires about their sexual health. The goal is to help healthcare provide…

This study is testing an artificial intelligence (AI) tool designed to help predict the success of fertility treatments like IVF. Researchers will use the tool to analyze 3D ultrasound images of ovaries to count egg-producing follicles and see if it can accurately forecast treatm…

This study looks at how searching for health information online affects stress and emotional well-being in women undergoing infertility treatment. Researchers will survey 201 women about their internet search habits, stress levels, and overall well-being during treatment. The goa…

This study is testing a new support program to help people from underserved communities get infertility care more quickly. A 'patient navigator' will help 40 participants schedule appointments, understand insurance, and complete required tests. The goal is to see if this extra gu…

This study aims to understand how pesticide exposure might be linked to endometriosis, a painful condition that can cause infertility. Researchers will compare 160 women with and without endometriosis, measuring stress markers in their blood and analyzing the bacteria in their gu…

This study aims to create a bank of ovarian tissue and a national database to better understand how cancer treatments affect fertility. It enrolls girls and women (ages 4-35) who are freezing ovarian tissue before starting cancer therapy. Researchers will store a small portion of…

This study is testing a new automated machine to freeze human eggs and embryos, comparing it to the current manual method performed by lab staff. It involves 125 people undergoing fertility treatment, using only surplus eggs and embryos that would otherwise be discarded. The main…

This study aims to find out if measuring a specific hormone (AMH) in the fluid surrounding a woman's egg during IVF can help predict whether the resulting embryo will have the correct number of chromosomes. Researchers will collect data from 300 women undergoing fertility treatme…

This study is testing a new automated system called AURA that handles sperm, eggs, and embryos during fertility treatments. It will compare results from the automated system to standard manual procedures to see if the machine works as well. The goal is to gather data on how well …

This study aims to understand how reproductive disorders like infertility, delayed puberty, or early puberty are inherited. Researchers will recruit 850 people with these conditions, along with their family members, to analyze their genes and medical histories. The goal is to ide…

This study aims to understand if low levels of a specific protein in the blood, called mannose binding lectin, are linked to repeated pregnancy loss or failed embryo implantation during fertility treatments. Researchers will measure this protein in 500 women who have experienced …

This study aims to see if artificial intelligence (AI) can analyze routine vaginal ultrasound images to predict whether a woman's uterine lining is ready for an embryo to implant during IVF. It involves about 1,500 women aged 18-40 undergoing IVF. The goal is to gather knowledge …