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Womb waves: could uterine contractions predict IVF success?

NCT ID NCT07675213

Knowledge-focused Sponsor: Mỹ Đức Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 30, 2026 · Last updated Jul 10, 2026 · Updated 4 times

Summary

This study looks at whether the natural contractions of the uterus (called endometrial peristalsis) influence the chance of pregnancy in women undergoing frozen embryo transfer with hormone replacement therapy. Researchers will measure these contractions using ultrasound at three key times during the treatment cycle. The goal is to see if certain contraction patterns are linked to higher live birth rates, which could help doctors personalize embryo transfer timing.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If a link is found, doctors may use uterine contraction patterns to time embryo transfers better, potentially improving pregnancy rates.
What could go wrong
This is an observational study, so it cannot prove cause and effect. The results may not lead to changes in practice.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 442 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2026

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Women undergoing hormone replacement therapy frozen embryo transfer during the study period

Ages

18 to 42 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Women aged 18 - 42 years old * Scheduled for frozen embryo transfer cycles using hormone replacement therapy protocol * Transferred no more than two cleavage embryos or one good-quality blastocyst or no more than two poor-quality blastocysts * Provision of written informed consent to participate Exclusion Criteria: * Having an allergy and contraindications for exogenous hormone administration (e.g., breast cancer, thromboembolic disease) * Cycles with preimplantation genetic testing, oocyte donation, or in vitro maturation * Having untreated uterine or adnexal abnormalities (e.g., intrauterine adhesions, unicornuate/ bicornuate/ arcuate uterus, endometrial polyp, large leiomyoma ≥5 cm in diameter, hydrosalpinx, endometrial hyperplasia) * Use of uterine relaxants or intralipid infusion during the embryo transfer process * Use of a GnRH-agonist for downregulation within one month

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Conditions

The condition(s) this trial relates to.

infertility disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Endometrial peristalsis Endometrial waves Frozen embryo transfer (FET) Hormone replacement therapy (HRT) Infertility Uterine contraction Uterine peristalsis

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • IVFMD - My Duc Hospital

    RECRUITING

    Ho Chi Minh City, 70000, Vietnam

More trials for these conditions

Other studies related to the condition(s) this trial covers.