INFERTILITY

This study is testing whether adding progesterone hormone support after fertility treatment improves pregnancy rates. It involves 690 women undergoing a specific fertility treatment (letrozole with intrauterine insemination) at clinics in Denmark. Participants will be randomly as…

This study is testing the safety of a new sperm preparation method for in vitro fertilization (IVF). It will compare the new method to standard procedures to see if it leads to healthier embryos and better pregnancy rates. The trial will involve about 200 couples undergoing IVF t…

This study is testing two different medications to see which one works better at helping men with low or no sperm counts produce more sperm. Researchers will compare a pill taken twice daily against hormone injections given three times a week over three months. The goal is to see…

This study is testing whether adding a specific Chinese herbal formula to standard ovulation therapy helps more women with diminished ovarian reserve get pregnant naturally. It will compare pregnancy rates between women receiving the combined treatment and those receiving standar…

This study aims to test how well a new artificial intelligence (AI) software tool works to help embryologists during IVF. The tool, called MAGENTA BLAST, analyzes images of embryos on Day 3 to predict which ones are most likely to develop into healthy blastocysts by Day 5. Resear…

This study is testing a new AI-powered tool called IntelliWell. It aims to find rare, usable sperm in testicular tissue samples from men with a severe form of infertility where no sperm is found in semen. If the AI successfully finds sperm that standard lab methods missed, those …

This study aims to test whether platelet-rich plasma (PRP) made from donated blood can improve sperm quality in men with infertility. Researchers will first develop a standard method to prepare the PRP, then test if adding it to sperm samples increases their movement and health. …

This study is testing whether a game-like mobile training program can help women feel more confident and adopt healthier habits while they go through stressful fertility treatments like IVF. Researchers will compare the app-based training to receiving just a booklet or standard c…

This study aims to understand if having tattoos affects pregnancy success in women undergoing IVF fertility treatments. Researchers will follow 328 women aged 21-40 who are having embryo transfers, comparing pregnancy outcomes between those with and without tattoos. The study wil…

This study aims to improve IVF success rates by using artificial intelligence (AI) to analyze time-lapse videos of developing embryos. Researchers will look back at data from 1,500 couples to find patterns in how embryos grow and move that predict which ones are most likely to im…

This study aims to understand what happens to couples after they go through IVF with genetic testing (PGT) to prevent passing on a severe inherited disease, but do not have a baby from the process. Researchers will follow 900 couples from a Paris clinic to learn about their emoti…

This study aims to understand why pregnancies from frozen embryo transfers have more complications like preeclampsia. Researchers will measure levels of a hormone called relaxin in 60 women who became pregnant through IVF. They want to see if different IVF methods affect this hor…

This study aims to understand how different microbes (like viruses and bacteria) are shared between partners and how they might affect fertility and pregnancy. Researchers will follow 200 couples who are having trouble conceiving, collecting samples from their mouths and genitals…

This study aims to understand if infertility or IVF treatments are linked to a higher risk of future heart and metabolic problems in women. Researchers will recruit 120 women in Manchester, some planning pregnancy and some who have already had a baby, to measure their heart and b…

This study aims to understand how the uterus's natural, wave-like contractions affect pregnancy success during frozen embryo transfers. Researchers will observe women undergoing two common fertility treatment protocols to see if specific contraction patterns are linked to higher …

This study aims to understand if having deep endometriosis in the bowel increases a person's risk of developing colorectal cancer. Researchers will enroll 30 female patients who are already scheduled for surgery to treat their bowel endometriosis. They will compare the genetic ac…